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Tadalafil + Dapoxetine

Written By Dr. Lipika KhuranaReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:37 AM (UTC)

Tadalafil + Dapoxetine Uses

Tadalafil+Dapoxetine is used in the treatment of premature ejaculation.

How Tadalafil + Dapoxetine works

Tadalafil + Dapoxetine is a combination of two medicines : Tadalafil and Dapoxetine, which treat premature ejaculation. Tadalafil is a phosphodiesterase type 5 (PDE 5) inhibitor which works by increasing blood flow to the penis during sexual stimulation and enables its erection following sexual stimulation. Dapoxetine is a selective serotonin reuptake inhibitor (SSRI) which increases the level of serotonin in nerves to improve control over ejaculation and increase the time taken to ejaculate.

Common side effects of Tadalafil + Dapoxetine

Nausea, Headache, Flushing (sense of warmth in the face, ears, neck and trunk), Dizziness, Diarrhea, Dyspepsia, Back pain, Muscle pain, Nasal congestion (stuffy nose), Limb pain
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Expert advice for Tadalafil + Dapoxetine

  • You have been prescribed Tadalafil + Dapoxetine for the treatment of premature ejaculation with erectile dysfunction.
  • Take it 1 to 3 hours before anticipated sexual activity.
  • Do not take it more than once every 24 hours or every day.
  • Do not drive or do anything requiring concentration until you know how Tadalafil + Dapoxetine affects you.
  • It may cause sudden drop in your blood pressure. Rise slowly if you have been sitting or lying down.
  • Inform your doctor if the erection persists for more than 4 hours after sexual intercourse.
  • Do not take Tadalafil + Dapoxetine if you have had a heart attack in the past 3 months, or stroke or heart failure in the past 6 months.

Frequently asked questions for Tadalafil + Dapoxetine

It should be taken approximately 1 to 3 hours before a sexual activity is anticipated. The effect may last for almost 4-5 hours, which is enough to complete the actual intercourse and to treat erectile dysfunction in most men.
No, taking Tadalafil+Dapoxetine may make you feel sleepy and dizzy. So, do not drive or use machines while taking this medicine.
Before you start taking Tadalafil+Dapoxetine tell your doctor if you have or have had heart problems such as a heart attack, irregular heartbeat, angina, chest pain or had heart surgery within the last 6 months. Inform you doctor if you have low blood pressure or uncontrolled high blood pressure.
Yes, the use of Tadalafil+Dapoxetine can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry.
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.