Information about Sulfadoxine

Sulfadoxine uses

Sulfadoxine is used in the treatment of malaria and bacterial infections.

How sulfadoxine works

Sulfadoxine is an antibiotic. It stops bacteria from producing folic acid, a vitamin required for bacterial replication.

Common side effects of sulfadoxine

Nausea, Vomiting, Skin rash, Allergic reaction.

Available Medicine for Sulfadoxine

No medicine available

Expert advice for Sulfadoxine

  • Take sulfadoxine along with food to minimize gastrointestinal side effects.
  • Take sulfadoxine with plenty of water to prevent crystalluria (crystals found in the urine when performing a urine test).
  • Avoid excessive sun exposure and wear protective clothing while taking sulfadoxine, as it may increase sensitivity to sunlight. 
  • Seek immediate medical attention if you experience signs of rash or any other allergic reaction or folate deficiency (low level of folic acid in the body).
  • You will be regularly monitored for complete blood count, liver function tests, analysis of urine for crystalluria if sulfadoxine is administered for > 3 months.
  • Do not drive or operate any machinery while taking sulfadoxine as it may cause dizziness.
  • Do not take if patient is allergic to sulfadoxine or any of its ingredients.
  • Do not take if patients with impaired kidney or liver function, blood dyscrasias (a diseased state of blood), folate deficiency, severe allergy or bronchial asthma, G6PD deficiency.
  • Do not given to Children less than 2 months.
  • Do not given to regnant women at term and breastfeeding women.

Content on this page was last updated on 19 May, 2017, by Dr. Varun Gupta (MD Pharmacology)