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Sofosbuvir + Velpatasvir

Written By Dr. Syeda AafiaReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:37 AM (UTC)

Sofosbuvir + Velpatasvir Uses

Sofosbuvir+Velpatasvir is used in the treatment of chronic hepatitis C virus (HCV) infection.

How Sofosbuvir + Velpatasvir works

Sofosbuvir + Velpatasvir is a combination of two antiviral medicines: Sofosbuvir and Velpatasvir. They work by lowering the amount of hepatitis C virus in the body and removing the virus from the blood over a period of time.

Common side effects of Sofosbuvir + Velpatasvir

Headache, Insomnia (difficulty in sleeping), Fatigue, Anemia (low number of red blood cells), Nausea, Vomiting, Weakness, Diarrhea, Rash
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Expert advice for Sofosbuvir + Velpatasvir

  • Sofosbuvir + Velpatasvir is used for the treatment of chronic hepatitis C virus (HCV) infection.
  • Take it with food, preferably at the same time everyday.
  • You will usually need to take this medicine every day for either 12 or 24 weeks.
  • Skipping doses increases the risk of treatment failure. Make sure that you take all your doses at the correct time.
  • It may cause fatigue, dizziness, and blurred vision. Don't drive or do anything requiring concentration until you know how it affects you.
  • Sofosbuvir + Velpatasvir may cause headaches. Drink plenty of water and take a suitable painkiller. Inform your doctor if it does not go away.
  • Your doctor may monitor your liver function and the amount of hepatitis C virus in your body regularly.Ā 
  • Do not stop takingĀ this medicine without your doctor’s advice.