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Selexipag

Written By Dr. Swati MishraReviewed By Dr. Rajeev Sharma
Last updated 05 Sep 2023 | 07:09 AM (UTC)

Selexipag Uses

Selexipag is used in the treatment of pulmonary arterial hypertension (PAH).

How Selexipag works

Selexipag acts on the blood vessels in lungs in a similar way to the natural substance prostacyclin, helping them to relax and widen. This makes it easier for the heart to pump blood through these blood vessels.

Common side effects of Selexipag

Headache, Diarrhea, Jaw pain, Nausea, Vomiting, Muscle pain, Pain in extremities, Flushing (sense of warmth in the face, ears, neck and trunk)
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Expert advice for Selexipag

  • Do not take Selexipag if you are allergic to Selexipag or any of the ingredients in this medicine.
  • Inform your doctor if you are taking medicines for high blood pressure or if you experience dizziness during treatment. Also, let the doctor know if you have severe kidney problems or are undergoing dialysis.
  • Inform your doctor if you are taking gemfibrozil (a medicine used to lower the level of fats [lipids] in the blood) since it may affect how Selexipag works and cause side effects.
  • Selexipag can cause side effects such as headaches and low blood pressure, avoid indulging in activities such as driving or operating machines.

Frequently asked questions for Selexipag

Selexipag is used to treat symptoms of pulmonary arterial hypertension, which is high blood pressure in the blood vessel that carries blood from the right side of the heart to the lungs.
Selexipag is an oral tablet given by mouth. The starting dose is 200 mcg twice daily. The dose is then increased by 200 mcg twice daily every week to the highest tolerated dose a patient can tolerate. The maximum dosage is 1600 mcg twice daily.
Swallow Selexipag tablet as a whole. Do not split, crush, or chew the tablet. If you miss a dose, take it as soon as you remember. If your next scheduled dose is due within six hours, skip the missed dose.
Before you take Selexipag, tell your doctor about all your medical conditions, including if you:<br>a. Have liver problems.<br>b. Are pregnant, breastfeeding, or plan to breastfeed.<br>c. Are taking any other prescription or over-the-counter medicines, vitamins, or herbal supplements.