Selenium is used as a dietary supplement mainly in the treatment of selenium deficiency affecting young women and children with Keshan disease. It is also used for treatment of osteoarthiritis associated with poor selenium levels in body called Kashin-Beck Disease. Selenium supplements are also used in patients with HIV/ AIDS to maintain the adequate selenium levels.
How it works
Selenium is a trace element that is essential in small amounts in the body. Selenium is important in the functioning of selenium dependent chemical (enzymes) in the body called as selanoproteins. Selenium is an integral part of glutathione peroxidases (GPx) that act as potent antioxidant (substance that protects against cell damage) by neutralizing the free radicals (waste products formed in the body during energy production) such as reactive oxygen and nitrogen species. Thus selenium participates in vital redox reactions of the body. Also, a selenoprotein (iodothyronine deiodinases) is essential for the conversion of thyroxine (T4) to the biologically active thyroid hormone triiodothyronine (T3) thereby indicating the importance of selenium in thyroid hormone functioning.
Common side effects
Nervous system disorder, Fatigue, Garlic breath odor, Irritation, Rash, Hair loss, Nail disorder
AVAILABLE MEDICINENo medicine available
Do not take this drug if you are allergic to selenium. Always consult your doctor before using selenium supplementation:
- If you have chronic kidney disease (or if you are on dialysis).
- If you have underactive thyroid.
- If you have skin cancer.
Do not take this medicine without consulting a doctor if you are pregnant or breast feeding. Using selenium long-term or at high doses may increase your risk of developing diabetes or other serious medical conditions. Ask your doctor about your specific risk.
Frequently asked questions
Q. Can I take selenium with synthyroid/ levothyroxine/ armour thyroid/ thyroxin?
There are no known interactions of selenium with any thyroid preparations such as synthyroid/ levothyroxine/ armour thyroid/ thyroxin. Selenium which is a part of selenoprotein (iodothyronine deiodinases) is essential for the conversion of thyroxine (T4) to the biologically active thyroid hormone triiodothyronine (T3) thereby it is important in thyroid hormone functioning.
Q. Can I take selenium with calcium?
There are no known interactions of selenium with minerals such as calcium.
Q. Can I take selenium with other vitamins/ vitamin C/ zinc?
Yes. Selenium (gluthathione peroxidase) has been reported to support the activity of vitamin E in limiting the oxidation of lipids (fats). Selenium also interacts with zinc (it affects cellular redox status). Selenium can, however, be taken with vitamins/ zinc; the combinations are available as a part of multivitamin preparation.
Q. Can I take selenium with statins?
There are no known interactions of selenium with statins. Always follow the advice of the doctor regarding its use.
Q. Can I take selenium with warfarin?
There are no known interactions of selenium with warfarin. Always follow the advice of the doctor regarding its use.