Information about Saxagliptin

Saxagliptin Uses

Saxagliptin is used to treat type-2 diabetes mellitus (T2DM) not controlled by diet and exercise alone and in whom metformin cannot be given due to contradiction or intolerance. If diabetes is not adequately controlled by insulin or other oral antidiabetic medicines (metformin, thiazolidinedione or sulphonylurea) or their combination, then saxagliptin can be used in a dual or triple medicine combination.
. It is used along with diet and exercise to improve blood sugar control in adults with type 2 diabetes.

How Saxagliptin works

Saxagliptin is an antidiabetic medication. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces the fasting and postmeal sugar levels.

Common side effects of Saxagliptin

Headache, Upper respiratory tract infection, Urinary tract infection, Abdominal pain, Diarrhea, Hypoglycemia (low blood glucose level), Nausea, Vomiting, Sinus inflammation, Edema (swelling)
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Reviewed By
MBA, MD Pharmacology
Last updated
13 Jun 2023 | 11:29 AM (UTC)

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Available Medicine for Saxagliptin

6652 variant(s)
SaxaquestMorepen Laboratories Ltd
190 to ₹1922 variant(s)
ZaxaglitChemo Healthcare Pvt Ltd
390 to ₹4322 variant(s)
SaglipolMedipol Pharmaceuticals India Pvt Ltd
380 to ₹5902 variant(s)
ZagliviaHauz Pharma Pvt Ltd
4301 variant(s)

Expert advice for Saxagliptin

  • Saxagliptin should be taken at the same time every day since this helps you remember to take it.
  • Be careful while driving or operating machinery until you know how Saxagliptin affects you.
  • It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor and anxiety.
  • Inform your doctor if you notice joint pains or develop symptoms such as stomach pain, nausea and/or vomiting.

Frequently asked questions for Saxagliptin


Q. Does Saxagliptin cause any weight loss (reduction)?

No, Saxagliptin neither causes weight loss nor weight gain. It is weight neutral. However, weight gain can be seen when Saxagliptin is used with other antidiabetic medicines like thiazolidinediones, sulfonylureas or insulin.

Q. What is the benefit of using Saxagliptin with insulin?

Saxagliptin when taken with insulin can help in lowering the insulin dose and decrease the risk of hypoglycemia (low blood sugar levels). Consult your doctor as a dose adjustment of the two may be needed.

Q. Are there any contraindications to the use of Saxagliptin?

Yes, the use of Saxagliptin is contraindicated in some conditions like a history of allergy to Saxagliptin, any ingredients of this drug or to any other drug of the same class. Saxagliptin should also be avoided in patients with a history of pancreatitis.

Q. Is it beneficial to use Saxagliptin with glipizide?

Yes, it is beneficial to take Saxagliptin and glipizide. Both are antidiabetic drugs, however, they work in different ways. When taken together, they can help in better controlling of blood sugar levels.

Q. Can Saxagliptin be used with other diabetes medicines?

Yes, Saxagliptin can be used alone or in combination with other diabetes medicines, along with proper diet and exercise.

Q. Can the use of Saxagliptin cause hypoglycemia (low blood sugar)?

Usually, Saxagliptin does not cause hypoglycemia when used alone in diabetes. However, it may cause low blood sugar when combined with other medicines like insulin and sulfonylureas.


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