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Roxatidine is used to treat gastritis (irritation and swelling of the inner lining of the gut), gastroesophageal reflux disease (irritation and swelling of the lining of the esophagus as a result of reflux of acids from stomach to esophagus causing heartburn) and ulcers in the gut (peptic ulcer).

How it works

Roxatidine belongs to a class of drugs called as H2 (histamine) receptor antagonists. It acts by reducing gastric acid secretion in the stomach by blocking a chemical known as histamine. 

Common side effects

Allergic skin rash, Constipation, Diarrhoea, Headache


Expert advice

  • Exercise caution while using roxatidine as it may mask the symptoms of gastric malignancy.
  • Always keep a gap of 2 hours between antacids (if required) and roxatidine, as the absorption of roxatidine is reduced by antacids.
  • Tell your doctor if you are pregnant or breast-feeding or planning to become pregnant.
  • Do not take if Patients is allergic to roxatidine or any of its ingredients.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)