Pyrimethamine + Sulfamethoxazole

Last updated 25 Nov 2025 | 09:37 AM (UTC)

Pyrimethamine + Sulfamethoxazole Uses

Pyrimethamine+Sulfamethoxazole is used in the treatment of malaria.

How Pyrimethamine + Sulfamethoxazole works

Pyrimethamine + Sulfamethoxazole is a combination of two medicines: Pyrimethamine and Sulfamethoxazole which treat malaria. Pyrimethamine is an antiparasitic medicine which works by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading. Sulfamethoxazole is an antibiotic which stops the bacteria from producing folic acid, a nutrient required for bacterial multiplication.

Common side effects of Pyrimethamine + Sulfamethoxazole

Diarrhea, Nausea, Vomiting, Fatigue, Feeling of fullness, Dizziness, Headache, Mouth sore, Skin rash

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Medicine brands for Pyrimethamine + Sulfamethoxazole

Lari

Ipca Laboratories Ltd

₹56 to ₹78

2 variant(s)

G Kelfin

Shrinivas Gujarat Laboratories Pvt Ltd

Mediwin Pharmaceuticals

₹25 to ₹25

1 variant(s)

Malazole

TOSC International Pvt Ltd

₹29 to ₹29

1 variant(s)

Malarwin

Wings Pharmaceuticals Pvt Ltd

Gujarat Terce Laboratories Ltd

₹18 to ₹18

1 variant(s)

Calfin

Redson Laboratories Pvt Ltd

₹27 to ₹27

1 variant(s)

Melar

Prayas Pharmaceuticals

₹8 to ₹8

1 variant(s)

Expert advice for Pyrimethamine + Sulfamethoxazole

Pyrimethamine + Sulfamethoxazole must be taken with food at the same time every day.
Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and harder to treat.
It is advisable to drink plenty of fluids and a healthy diet while taking the medicine.
It may cause dizziness. Do not drive or do anything that requires mental focus until you know how the medicine affects you.
Avoid consuming alcohol while taking medication as it may cause increased side effects.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Frequently asked questions for Pyrimethamine + Sulfamethoxazole

Q. What if I don't get better after using Pyrimethamine+Sulfamethoxazole?

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

Q. Can I stop taking Pyrimethamine+Sulfamethoxazole when I feel better?

No, do not stop taking Pyrimethamine+Sulfamethoxazole and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

Q. What if I miss my dose?

Take Pyrimethamine+Sulfamethoxazole as soon as you remember it. However, do not take it if it's almost time for your next dose. Also, do not take an extra dose to make up for your missed dose.