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Prednisolone

Written By Dr. Swati MishraReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:34 AM (UTC)

Prednisolone Uses

Prednisolone is used in the treatment of severe allergic reactions, allergic conditions, rheumatic disorder, skin disorders, eye disorders and nephrotic syndrome.

How Prednisolone works

Prednisolone is a steroid which works by blocking the production of certain chemical messengers in the body that cause inflammation (redness and swelling) and allergies.

Common side effects of Prednisolone

Reduction in bone density, Upset stomach, Behavioral changes, Mood changes, Weight gain
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Expert advice for Prednisolone

  • Prednisolone helps treat inflammation, severe allergies, flare-ups of ongoing illnesses, and many other medical problems that require either reduction of inflammation or suppression of the immune system.
  • Do not use it more often or for longer than advised by your doctor.
  • Take it with food to avoid an upset stomach.
  • Prednisolone can make it harder for you to fight off infections. Notify your doctor if you have any signs of infection such as a fever or sore throat.
  • Side effects such as mood changes or stomach problems can happen when you start taking Prednisolone. Inform your doctor if this bothers you.
  • Do not stop taking Prednisolone suddenly without talking to your doctor first as it may worsen your symptoms.

Frequently asked questions for Prednisolone

Prednisolone belongs to the class of corticosteroids which has anti-inflammatory properties. It works by suppressing the inflammation associated with many diseases, for example, arthritis. Therefore, Prednisolone is used for the treatment of a number of inflammatory and auto-immune conditions.
It is advisable to take Prednisolone for the duration prescribed by your doctor. Do not stop the treatment suddenly or take for a longer period than recommended by your doctor.
No, Prednisolone does not contain penicillin. Prednisolone belongs to a group of medicines called steroids.
Yes, Prednisolone does expire. All the medicines come with an expiry date mentioned on the pack. You must check the expiry date before using any medicine.
No, Prednisolone is not a painkiller. Prednisolone belongs to a group of medicines called steroids which are anti-inflammatory in nature. The medicine can help in pain relief which is caused due to inflammation.
Prednisolone is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Prednisolone has immunosuppressant properties which means it suppresses the body’s immune system. Hence, Prednisolone is used for the treatment of a number of inflammatory and auto-immune conditions.
Yes, Prednisolone is a glucocorticoid. It belongs to a group of medicines called steroids (corticosteroids).
Certain antibiotics may increase the metabolism of Prednisolone and hence decrease its effects. So, if you are already taking antibiotics then it may be necessary to adjust the dose of Prednisolone accordingly. Hence, consult your doctor before taking Prednisolone with antibiotics.
Yes, Prednisolone can be taken with paracetamol. No drug-drug interactions have been reported when used together. However, in some cases interactions may occur. Please consult your doctor before taking the two medicines together.