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Prednisolone is a steroid used to reduce inflammation associated with various disorders such as allergies, rheumatoid arthritis, blood disorders, gastro-intestinal disorders, respiratory diseases, cancer and skin disorders.Prednisolone is also used as eye drops   to treat eye swelling caused by allergy, infection, injury, surgery, or other conditions

How it works

Prednisolone belongs to a group of medicines called as glucocorticosteroids. Prednisolone increases the level of corticosteroids which are already present in the body and helps to treat various inflammatory conditions. It has anti-inflammatory, metabolic, immune, and hormonal effects on the body.

Common side effects

Personality changes, Acne, Altered blood lipids, Altered menstrual cycle, Absence of menstrual periods, Behavioual changes, Decreased sexual function, Decreased libido, Delayed wound healing, Dizziness, Eye swelling, Fatigue, Fragile skin, Happiness, Headache, Heartburn, Increased hair growth, Increased sweating, Insomnia, Mood changes, Muscle stiffness, Muscle weakness, Skin redness


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Expert advice

  • Do not take the medicine if you are allergic to it or to any other content in the medicine.Inform your doctor: If you have heart, kidney or liver disease, mental disorders or depression, mania or bi-polar disorder, If you are pregnant or planning to become pregnant or breast-feeding a baby.
  • Do not drive or operate heavy machinery if you experience low level of alertness after taking prednisolone. The drug  can weaken your immune system, making it easier for you to get an infection or worsening an infection you already have or have recently had. Avoid being near people who are sick or have infections.
  • Do not receive a "live" vaccine while using prednisolone.
  • Do not stop using prednisolone suddenly, or you could have unpleasant withdrawal symptoms. Do not keep the eye drops in freezer.
  • Do not stop using prednisolone eye drops suddenly after long-term use without first talking to your doctor.
  • Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Frequently asked questions


Q. Is prednisolone a steroid, pain-killer, or an anti-inflammatory drug?
Prednisolone is a steroid anti-inflammatory drug. However, it is not a pain-killer.
Q. Is prednisolone the same as prednisone?
No. Prednisolone is the active metabolite of prednisone. Both of them are corticosteroids used for different indications.
Q. Can I take prednisolone for whooping cough or chest infection?
No, prednisolone is not used for whooping cough or chest infection.
Q. Is prednisolone safe?
Yes. Prednisolone is relatively safe if used as recommended. In case of any side-effects, consult your doctor.
Q. How long can I take corticosteroids for?
It is advisable to take the drug for the duration prescribed by your doctor. Do not stop the treatment abruptly or take for a longer period than recommended.
Q. Does prednisolone cause hair loss, weight gain, tiredness, acne, or drowsiness?
Yes. Prednisolone may cause hair loss, weight gain, tiredness, acne or drowsiness. If you experience any such symptoms, please consult your doctor.

Content on this page was last updated on 14 October, 2016, by Dr. Varun Gupta (MD Pharmacology)