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Praziquantel is used to treat schistosoma (infection with a type of worm that thrives in the blood stream) and liver fluke (infection with a type of worm that thrives in or near the liver). It may also be used to treat some other worm infestations like tapeworm (a type of worm in the intestine that may move to other parts of the body).

How it works

Praziquantel belongs to a class of medication called anthelmintics (anti-worm). It affects the permeability of the cell membrane thereby killing the  worms.

Common side effects

Dizziness, Itching, Fever, Headache, Feeling of discomfort, Nausea, Stomach pain


Expert advice

  • Inform your doctor if you have liver, kidney or heart problems or worm infection in the brain; history of seizures.
  • Do not drive or operate machinery as praziquantel may cause sleepiness and may impair your ability to think or react.
  • Use praziquantel with caution if you are an elderly patient.
  • Praziquantel is not recommended in children below 4 years of age.

Frequently asked questions


Q. Is praziquantel an antibiotic?
No, praziquantel is not an antibiotic.
Q. Is praziquantel over the counter/ safe for humans/ FDA approved?
Praziquantel is available only on prescription and is FDA approved. It is safe for humans at a dose and for a duration recommended by your doctor for your specific condition.
Q. Does praziquantel kill roundworm/ tapeworm/ hookworm/ whipworm?
Praziquantel is known to kill roundworm/ tapeworm/ hookworm. It is not known to kill whipworm.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)