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Potassium Citrate

INFORMATION

Uses

Potassium Citrate is used in the treatment of nutritional defeciencies.

How it works

The metabolism of absorbed citrate produces an alkaline load. The induced alkaline load in turn increases urinary pH and raises urinary citrate by augmenting citrate clearance without measurably altering ultrafilterable serum citrate. Thus, potassium citrate therapy appears to increase urinary citrate principally by modifying the renal handling of citrate, rather than by increasing the filtered load of citrate. The changes induced by potassium citrate tablets produce a urine that is less conducive to the crystallization of stone-forming salts (calcium oxalate, calcium phosphate and uric acid). Increased citrate in the urine, by complexing with calcium, decreases calcium ion activity and thus the saturation of calcium oxalate. Citrate also inhibits the spontaneous nucleation of calcium oxalate and calcium phosphate (brushite).

Common side effects

Paralysis, Abdominal pain, Allergic reaction, Diarrhoea, Nausea, Vomiting

AVAILABLE MEDICINE

No medicine available

Content on this page was last updated on 28 September, 2016, by Dr. Varun Gupta (MD Pharmacology)