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    Paracetamol/Acetaminophen

    Information about Paracetamol/Acetaminophen

    Paracetamol/acetaminophen uses

    Paracetamol/Acetaminophen is used for pain relief and fever. It is used to relieve pain in conditions like headache, muscle pain, or dental pain.

    How paracetamol/acetaminophen works

    Paracetamol/Acetaminophen is an analgesic (pain reliever) and anti-pyretic (fever reducer). It works by blocking the release of certain chemical messengers that cause pain and fever.

    Common side effects of paracetamol/acetaminophen

    No common side effects seen

    Available Medicine for Paracetamol/Acetaminophen

    • ₹2 to ₹39
      Glaxo SmithKline Pharmaceuticals Ltd
      6 variant(s)
    • ₹14 to ₹268
      Micro Labs Ltd
      7 variant(s)
    • ₹10 to ₹177
      Alkem Laboratories Ltd
      8 variant(s)
    • ₹179 to ₹340
      Fresenius Kabi India Pvt Ltd
      2 variant(s)
    • ₹14 to ₹366
      Veritaz Healthcare Ltd
      7 variant(s)
    • ₹14 to ₹60
      GlaxoSmithKline Consumer Healthcare
      8 variant(s)
    • ₹9 to ₹273
      East India Pharmaceutical Works Ltd
      8 variant(s)
    • ₹9 to ₹389
      Abbott
      5 variant(s)
    • ₹9 to ₹222
      Ipca Laboratories Ltd
      8 variant(s)
    • ₹9 to ₹38
      Mankind Pharma Ltd
      4 variant(s)

    Expert advice for Paracetamol/Acetaminophen

    • Good for pain relief and fever but not effective in joint pain due to poor anti-inflammatory action.
    • Starts working within one hour. Wait for at least 4 hours before taking the next dose.
    • Present in many over-the-counter (OTC) and prescription medicines. Avoid taking more than one paracetamol product at a time to prevent overdose. Doses >4 g/day (2 g in alcoholics) may cause liver, kidney or heart problems.
    • Discontinue Paracetamol/Acetaminophen and inform your doctor immediately if rash occurs.
    • For children, measure the doses of liquid Paracetamol/Acetaminophen using the measuring cup instead of a teaspoon to avoid under or over-dosage.
    • Avoid excess alcohol intake (>3 glasses/day) when taking Paracetamol/Acetaminophen as it may cause liver damage.

    Frequently asked questions for Paracetamol/Acetaminophen

    Paracetamol/Acetaminophen

    Q. When will I feel better after taking Paracetamol/Acetaminophen?

    Paracetamol/Acetaminophen begins to ease pain and reduces fever in about 45 minutes after a dose is taken. Its effects last for about 5 hours.

    Q. Can I take Paracetamol/Acetaminophen with vitamin B complex?

    Yes, Paracetamol/Acetaminophen can be taken with vitamin B-complex preparations. They have been used together in the treatment of acute and painful diseases affecting nerves like trigeminal neuralgias, post-operative pain, etc. Paracetamol/Acetaminophen helps to relieve pain and vitamin B-complex corrects the deficiency that might be causing your symptoms.

    Q. Is Paracetamol/Acetaminophen use associated with Helicobacter pylori infection?

    No, Paracetamol/Acetaminophen use is not associated with Helicobacter pylori infection. Painkiller drugs can increase the acid secretion in the stomach, aggravate the symptoms of this infection and the risk of stomach and the intestine ulcer. However, this risk is minimum with Paracetamol/Acetaminophen as compared to other pain killers.

    Q. Can I take Paracetamol/Acetaminophen with warfarin?

    Paracetamol/Acetaminophen is safe to use occasionally with warfarin as other painkillers like ibuprofen and aspirin can increase the risk of bleeding. However, on a long-term use, Paracetamol/Acetaminophen can also increase the risk of bleeding. Talk to your doctor before taking them together as you may need to be monitored regularly.

    Q. Can anyone be allergic to Paracetamol/Acetaminophen?

    Yes, there have been reports of hypersensitivity and allergic reaction with the use of Paracetamol/Acetaminophen. Symptoms of an allergy include swelling of the face, mouth, and throat, shortness of breath, urticaria, red rash, and severe itching. Stop taking Paracetamol/Acetaminophen if you have such symptoms and immediately consult your doctor.

    Q. How beneficial is to use Paracetamol/Acetaminophen with diclofenac?

    Paracetamol/Acetaminophen and Diclofenac might be given together in case of fever and pain. Paracetamol/Acetaminophen has an early onset of action and it helps in relieving the symptoms till diclofenac starts working. However, both are pain killers and can affect stomach lining on long-term use leading to acid reflux, hea<br>rtburn, and stomach ulcers and bleeding.

    Q. Does Paracetamol/Acetaminophen treat sore-throat, flu or cold?

    Paracetamol/Acetaminophen does not treat sore-throat, flu or cold but it can help in relieving fever and body aches associated with these conditions.

    Q. Can I take Paracetamol/Acetaminophen with amoxicillin?

    Paracetamol/Acetaminophen and amoxicillin can be taken together. Amoxicillin is an antibiotic and is used to treat bacterial infections. Paracetamol/Acetaminophen is given along, for the relief of any associated pain and fever. No drug-drug interactions or any harmful effects have been reported when they are used together.

    Q. Does Paracetamol/Acetaminophen have side effects?

    Paracetamol/Acetaminophen is quite safe for short term use. It has side effects if taken in more than the dose advised and for a long-term. Immediately consult a doctor if there is nausea, stomach pain, loss of appetite, dark colored urine, clay colored stools or jaundice as it could be due to an overdose of Paracetamol/Acetaminophen.

    Q. Is Paracetamol/Acetaminophen safe to use?

    Paracetamol/Acetaminophen is safe to use in the dose that advised by the doctor. Using this medicine in more than recommended doses can damage your liver and cause serious harm.

    Q. Can I take Paracetamol/Acetaminophen with homeopathic medicine?

    Ask your doctor before taking Paracetamol/Acetaminophen with homeopathic medicine as there is no information available on this.

    Q. Is it safe to take Paracetamol/Acetaminophen with Tramadol?

    Yes, Paracetamol/Acetaminophen can be taken with Tramadol. They are used together for moderate to severe pain in various diseases and their use is associated with common side effects like nausea, dizziness, and sleepiness.No drug-drug interactions have been reported when they are used together.

    Q. Can I take Paracetamol/Acetaminophen with Azithromycin?

    Paracetamol/Acetaminophen and Azithromycin can be taken together. Azithromycin is an antibiotic and is used to treat bacterial infections. Paracetamol/Acetaminophen is given along, for the relief of any associated pain and fever. No drug-drug interactions or any harmful effects have been reported when they are used together.

    Q. Can a patient with high blood pressure take Paracetamol/Acetaminophen?

    Occasional use of Paracetamol/Acetaminophen is safe in patients with high blood pressure. However, if it is to be taken for a long time, you must talk to your doctor. Paracetamol/Acetaminophen belongs to the group of painkillers called analgesics and antipyretics and these drugs can decrease the action of medicines taken by the patient for control of high blood pressure.

    Q. What happens if you take an overdose of Paracetamol/Acetaminophen?

    Overdose of Paracetamol/Acetaminophen can cause potentially life-threatening liver damage, which is the most serious side effect. Early symptoms may include nausea, vomiting, profuse sweating, and general tiredness. Kidney damage, decreased platelet count and coma may also occur. Immediately consult a doctor or consult an emergency in the case of suspected overdosage.

    Q. Can vitamin D be taken safely with Paracetamol/Acetaminophen?

    Yes, vitamin D can be taken with Paracetamol/Acetaminophen. Patients with osteoarthritis who are on vitamin D and calcium may need to take Paracetamol/Acetaminophen for the relief of any associated pain. No drug-drug interactions or any harmful effects have been reported.

    Q. Does Paracetamol/Acetaminophen affect the liver?

    Use of Paracetamol/Acetaminophen for a long time and above recommended doses can cause liver damage ranging from abnormal liver tests to liver failure. If you are taking Paracetamol/Acetaminophen from a long time and have nausea, stomach pain, loss of appetite, dark colored urine, clay colored stools or jaundice, inform your doctor as these could be signs of an underlying liver damage.

    Q. Can I take Paracetamol/Acetaminophen if I have hepatitis?

    Paracetamol/Acetaminophen is considered the safest painkiller to take for people with hepatitis for mild to moderate pain and fever. However, Paracetamol/Acetaminophen is metabolized in the liver, so, consult your doctor before taking Paracetamol/Acetaminophen if you have hepatitis as it can cause liver damage if taken in higher doses or for a very long time.

    Q. What are the serious side effects of taking excess Paracetamol/Acetaminophen?

    Potentially severe life-threatening liver injury is a serious side effect seen with an overdose of Paracetamol/Acetaminophen. Overdose can also cause kidney injury, coma, and decreased platelet count. Early symptoms of an overdose include nausea, vomiting, and general tiredness. Immediately consult a doctor or reach an emergency in case of suspected overdose.

    Q. How long does Paracetamol/Acetaminophen takes to work?

    Paracetamol/Acetaminophen takes around 30-45 min to start working and show its effects.

    Q. What is the recommended dose of Paracetamol/Acetaminophen?

    In adults, the usual dose is 1-2 tablets i.e 500mg or 650mg. The minimum dosing interval should be of 4 hours between the doses. The total dose should not exceed 4g per day.

    Q. Can the use of Paracetamol/Acetaminophen make me feel sleepy?

    No, Paracetamol/Acetaminophen does not cause sleepiness.

    Q. How much Paracetamol/Acetaminophen can you take in a day?

    In adults, the total dose of Paracetamol/Acetaminophen should not exceed 4g per day. In children, the maximum dose should not exceed 60mg/kg in a day.

    Content on this page was last updated on 04 January, 2019, by Dr. Varun Gupta (MD Pharmacology)