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Nitroxazepine is prescribed for depression, and inability to control urination at night time (nocturnal enuresis).

How it works

Nitroxazepine is a tricyclic antidepressant (TCA). It inhibits the re-uptake of certain chemicals (noradrenaline and serotonin) in the central nervous system, resulting in an antidepressant effect.

Common side effects

Nausea, Abnormal heart rhythm, Blurred vision, Confusion, Constipation, Decreased blood pressure, Dizziness, Drowsiness, Dry mouth, Difficulty in urination, Headache, Impotence, Jaundice, Decreased white blood cell count, Loss of appetite, Loss of libido, Rash, Sedation, Vomiting


Expert advice

  • Caution should be exercised in patients with history of mental illness, any allergy, kidney or liver problems, diabetes, suicidal thoughts, myocardial infarction and congestive heart failure, alcoholism, who are taking other medications and in elderly and children.
  • Tell your doctor if you are or planning to become pregnant or are breast-feeding.
  • Contact your doctor immediately if you experience any allergic reaction.
  • Nitroxazepine may cause drowsiness, dizziness, or blurred vision; do not drive a car or operate machinery while taking this medication.
  • Do not drink alcohol while taking this medication.
  • Do not stop using nitroxazepine suddenly unless prescribed by your doctor, or you could have unpleasant withdrawal symptoms.
  • Avoid exposure to sunlight while taking this medication.

Frequently asked questions


Q. Is nitroxazepine safe?
Nitroxazepine is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is Nitroxazepine the same as diazepam?
No. Nitroxazepine is primarily prescribed for depression, and bedwetting; while diazepam is used to treat anxiety disorders, alcohol withdrawal symptoms, or muscle spasms.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)