Information about Nitroxazepine

Nitroxazepine Uses

Nitroxazepine is used in the treatment of depression. It is used in patients intolerant of or unresponsive to other treatment options for depression.

How Nitroxazepine works

Nitroxazepine is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

Common side effects of Nitroxazepine

Increased heart rate, Difficulty in urination, Constipation, Weight gain, Dryness in mouth, Orthostatic hypotension (sudden lowering of blood pressure on standing)
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MD (Pharmacology), MBBS
Last updated
12 Sep 2022 | 06:59 AM (UTC)

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Frequently asked questions for Nitroxazepine


Q. What is Nitroxazepine used for?

Nitroxazepine belongs to a class of medicines known as tricyclic antidepressants and is used to treat depression. It restores the chemical imbalance in the brain and improves the mood and behavior. It is also used to treat bedwetting in children older than 6 years of age.

Q. What are the side effects of Nitroxazepine?

The side effects of Nitroxazepine are increased heart rate, blurred vision, dryness in mouth, weight gain, difficulty in urination, constipation and orthostatic hypotension (sudden decrease in blood pressure on standing). Please consult your doctor if these side effects do not go away or worry you.

Q. Can I just stop taking Nitroxazepine?

No, you must not stop taking Nitroxazepine suddenly even if you are feeling better as it may worsen your condition and also cause withdrawal symptoms such as dizziness, nausea, vomiting, headache, weakness, sleep problems, fever, and irritability. Continue taking Nitroxazepine for the duration as prescribed by your doctor to get maximum benefit. If any of the side effects are bothering you, consult your doctor. In case you have completed your course of treatment, your doctor will reduce your dose gradually before taking you off this medicine completely.

Q. Can a pregnant woman take Nitroxazepine?

Do not take Nitroxazepine during pregnancy unless recommended by the doctor. If you take this medicine during the last trimester of the pregnancy, the newborn may develop symptoms such as breathing problems, weakness, irritability, changes in blood pressure, tremors, and spasms. Studies have shown significant risks to the developing baby and it is given only if the benefits are clearly more than the risks involved. It is advised that you should consult your doctor before taking this medicine if you are pregnant, planning to become pregnant or breastfeeding.

Q. Does Nitroxazepine make you sleepy?

Yes, Nitroxazepine may make you feel sleepy. It is therefore advised that you do not drive, use any heavy machinery or do any work that requires concentration while taking Nitroxazepine. Also, refrain yourself from taking alcohol if you are being treated with Nitroxazepine as it will increase your drowsiness.

Q. Is there anything I need to be careful about while on treatment with Nitroxazepine?

Nitroxazepine may cause drowsiness and dizziness, especially in the beginning of the treatment. Do not drive or work with tools or machinery if your alertness is affected. It is not advisable to drink alcohol during treatment with this medicine as it might worsen the drowsiness. Let your doctor know if you have any problems with your liver or kidneys. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Inform your doctor if you are pregnant, planning to conceive or breastfeeding to prevent any harmful effects on the baby.


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