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Natural Micronised Progesterone



Natural Micronised Progesterone is used in hormone replacement therapy (hrt)

How it works

Progesterone belongs to a class of medications called progestins (female hormones). It is used as a part of hormone replacement therapy to bring on the menstruation by decreasing the levels of estrogen in the uterus and replacing the natural progesterone in women who are lacking.

Common side effects

Rash, Adrenal insufficiency, Vaginal discharge, Headache, Dizziness, Back pain, Increased appetite, Decreased libido, Pain in extremity, Abdominal distension, Sleepiness, Cushing syndrome, Vomiting, Nausea, Edema, Abdominal pain, Lower abdominal pain, Breast pain, Hair loss, Fatigue, Acne, Hot flushes, Thrombophlebitis, Diarrhoea, Irregular menstrual cycle, Cushingoid syndrome, Increased blood pressure, Depression, Mood changes, Nervousness, Constipation, Increased glucose level in blood, Breathing difficulty

Available Medicine

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Expert advice

  • Progesterone should be taken on an empty stomach or at least one hour before food or two hours after food.
  • Do not take progesterone and consult your doctor if you have ever had any unexpected and unexplained bleeding from your vagina which was not due to your normal monthly period.
  • Consult your doctor if you are pregnant, think you may be pregnant or planning a family before taking progesterone.
  • Do not take progesterone without informing your doctor if you are breast-feeding.
  • Do not drive a motor vehicle or operate a machine immediately after taking progesterone. You may experience a temporary (1 to 3 hours) feeling of sleepiness and dizziness after taking progesterone. 
  • Oral progesterone should preferably be taken at bedtime.
  • Consult  your doctor about any severe stomach pain or yellowing of your eyes or skin.
  • Immediately consult your  if you have sudden vision changes or one-sided weakness (signs of stroke) or chest pain and trouble breathing (signs of a pulmonary embolism).

Frequently asked questions

Natural Micronised Progesterone


What is natural micronised progesterone?
These are natural progesterone preparations which have improved bioavailability and fewer side effects compared with synthetic progesterone.

Content on this page was last updated on 27 March, 2017, by Dr. Varun Gupta (MD Pharmacology)