1mg, best e pharmacy in India




Misoprostol is used to prevent gastric ulcers resulting from treatment with pain-killers/NSAIDs (non-steroidal anti-inflammatory drugs like ibuprofen, naproxen, indomethacin). It is also used for medical termination of pregnancy or legal abortion during early pregnancy, along with mifepristone.

How it works

Misoprostol is similar to the natural chemical prostaglandin found in the body. It acts on the stomach and intestine to create a protective lining, and thereby prevents ulcer formation. It also acts on the uterus and produces strong contractions and softens the cervix to cause abortion.

Common side effects

Constipation, Flatulence, Headache, Indigestion, Stomach pain, Vomiting, Diarrhoea


Showing 10 of 33

Expert advice

  • Misoprostol should only be given to adults (above 18 years of age).
  • If you are taking misoprostol for abortion, it is important to take it 36-48 hours after taking mifepristone. Rest for at least 3 hours after taking this tablet.
  • Do not take misoprostol tablet if you are allergic to it or to any other content in the medicine.
  • Avoid using misoprostol if you are pregnant or planning to become pregnant or breastfeeding.
  • Do not drive a vehicle or operate heavy machinery after taking this drug as it may cause dizziness.
  • Doctor’s advice should be considered in case of patients with following history of disease conditions: liver, heart, kidney disease, inflammatory bowel disease, diabetes, anaemia, problems with clotting of blood, abnormal blood pressure or cholesterol or suffer from malnutrition.
  • Do not smoke cigarrete while taking misoprostol.

Frequently asked questions


Q. Is misoprostol safe?
Yes. Misoprostol is relatively safe if used as recommended. In case of any side-effects, consult your doctor.
Q. Is misoprostol available or sold over the counter?
No. Misoprostol is a prescription drug. It is not available or sold over the counter.
Q. Is misoprostol effective orally?
Yes. Misoprostol is effective orally.
Q. Is misoprostol available and legal in India?
Yes. Misoprostol is legally available in India.
Q. Can I take misoprostol with Advil, Vicodin, hydrocodone?
Misoprostol may be taken with Advil (ibuprofen), Vicodin (paracetamol and hydrocodone), and hydrocodone if prescribed by your doctor.
Q. Does misoprostol cause weight gain?
There is no evidence of misoprostol causing weight gain. If you notice any such symptoms, please consult your doctor.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)