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Methylcobalamin + Pregabalin

Information about Methylcobalamin + Pregabalin

Methylcobalamin + Pregabalin Uses

Methylcobalamin+Pregabalin is used in the treatment of neuropathic pain.

How Methylcobalamin + Pregabalin works

Methylcobalamin + Pregabalin is a combination of two medicines: Methylcobalamin and Pregabalin. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Pregabalin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).

Common side effects of Methylcobalamin + Pregabalin

Dizziness, Sleepiness, Headache, Nasopharyngitis (inflammation of the throat and nasal passages), Increased appetite, Confusion, Disorientation, Abnormality of voluntary movements, Balance disorder (loss of balance), Lethargy, Blurred vision, Vertigo, Vomiting, Constipation, Muscle cramp, Edema (swelling), Erectile dysfunction, Weight gain
Written By
Reviewed By
MD (Pharmacology), MBBS
Last updated
23 Jun 2022 | 04:38 PM (UTC)

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Available Medicine for Methylcobalamin + Pregabalin

Pregeb MTorrent Pharmaceuticals Ltd
199 to ₹3154 variant(s)
Pregalin MTorrent Pharmaceuticals Ltd
251 to ₹3104 variant(s)
Maxgalin MSun Pharmaceutical Industries Ltd
137 to ₹2706 variant(s)
Neugaba MSun Pharmaceutical Industries Ltd
114 to ₹2813 variant(s)
NeurotratZydus Cadila
8 to ₹1534 variant(s)
Pregalin XTorrent Pharmaceuticals Ltd
158 to ₹2872 variant(s)
Mahagaba-MMankind Pharma Ltd
139 to ₹1492 variant(s)
AxogurdAlembic Pharmaceuticals Ltd
184 to ₹1922 variant(s)
Revlin MEris Lifesciences Ltd
173 to ₹2863 variant(s)
224 to ₹2382 variant(s)

Expert advice for Methylcobalamin + Pregabalin

  • You have been prescribed Methylcobalamin + Pregabalin for treating and preventing nerve pain.
  • Its side effects are usually mild and temporary.
  • It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • To lower the chances of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Avoid consuming alcohol when taking Methylcobalamin + Pregabalin, as it may cause excessive sleepiness.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression or suicidal thoughts or behavior.
  • Do not stop taking the medication suddenly without talking to your doctor.

Frequently asked questions for Methylcobalamin + Pregabalin

Methylcobalamin + Pregabalin

Q. What is Methylcobalamin+Pregabalin?

Methylcobalamin+Pregabalin is a combination of two medicines: Pregabalin and Methylcobalamin. This medicine is useful in the treatment of nerve pain (neuropathic pain). It calms the damaged or overactive nerves by acting on the brain, thereby decreasing the pain sensation. It also helps in the regeneration of damaged nerves in the body.

Q. Can I stop taking Methylcobalamin+Pregabalin when my pain is relieved?

No, you should not stop taking Methylcobalamin+Pregabalin even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Methylcobalamin+Pregabalin, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the use of Methylcobalamin+Pregabalin before you stop the medication completely.

Q. How to manage weight gain associated with the use of Methylcobalamin+Pregabalin?

Methylcobalamin+Pregabalin can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight. However, preventing weight gain is easier than losing the increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). Do not eat food items that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits, and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will help prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.

Q. Can the use of Methylcobalamin+Pregabalin cause sleepiness or drowsiness?

Yes, Methylcobalamin+Pregabalin may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medicine affects you. Inform your doctor if you experience such episodes while you are taking this medicine.

Q. Are there any serious side effects associated with the use of Methylcobalamin+Pregabalin?

Serious side effects caused because of the use of Methylcobalamin+Pregabalin are uncommon and rare. However, it may cause serious side effects like allergic reaction, suicidal thoughts or swelling of limbs (hands, legs or feet). Stop taking Methylcobalamin+Pregabalin and contact your doctor if you have any signs of these serious side effects. Signs of an allergic reaction include swelling of your face, mouth, lips, gums, tongue and neck. Allergic reactions can also lead to trouble in breathing, skin rash, hives (raised bumps) or blisters. Pay attention to any changes, especially sudden changes in mood, behaviors, thoughts or feelings, or if you have suicidal thoughts.

Q. How long will the Methylcobalamin+Pregabalin take to act?

An initial benefit with Methylcobalamin+Pregabalin may be seen after 2 weeks of treatment. However, it may take around 2-3 months or more (in some patients) to see the full benefits.

Q. What if I forget to take Methylcobalamin+Pregabalin?

If you forget to take the scheduled dose of Methylcobalamin+Pregabalin and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effects. If you are not sure what to do, consult your doctor about how to manage a situation like this.

Q. Will a higher than the recommended dose of Methylcobalamin+Pregabalin be more effective?

No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.

Q. Can I drink alcohol while taking Methylcobalamin+Pregabalin?

No, do not drink alcohol while taking Methylcobalamin+Pregabalin. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Methylcobalamin+Pregabalin.

Q. How often should I see the doctor ?

You may need to see your doctor regularly if you have started to take Methylcobalamin+Pregabalin. However, you must consult your doctor if the advised dosage of Methylcobalamin+Pregabalin does not improve your symptoms or you continue experiencing some unwanted side effects that affect your routine activities.

Q. Are there any special instructions regarding storage and disposal of this medicine?

Keep your tablets in the pack until it is time to take them. Store them in a cool dry place. Store them out of sight and reach of children. Unused medications should be disposed of in special ways to ensure that pets, children and other people cannot consume them.


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