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Menthol

Information

Uses

Menthol is used in the treatment of dermatitis, itching and eczema.

How it works

Menthol primarily activates the cold-sensitive TRPM8 receptors in the skin. Menthol, after topical application, causes a feeling of coolness due to stimulation of 'cold' receptors by inhibiting Ca++ currents of neuronal membranes. It may also yield analgesic properties via kappa-opioid receptor agonism.

Common side effects

Balance disorder (loss of balance), Vomiting, Altered heart rate, Drowsiness, Hypersensitivity reaction, Nausea, Abdominal pain, Contact dermatitis, Skin irritation, Apnea (absence of breathing), Nystagmus (involuntary eye movement), Vertigo, Coma

Available Medicine

No medicine available

Content on this page was last updated on 20 February, 2017, by Dr. Varun Gupta (MD Pharmacology)