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Losartan + Amlodipine + Hydrochlorothiazide

Written By Dr. Anuj SainiReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:37 AM (UTC)

Losartan + Amlodipine + Hydrochlorothiazide Uses

Losartan+Amlodipine+Hydrochlorothiazide is used in the treatment of Hypertension (high blood pressure).

How Losartan + Amlodipine + Hydrochlorothiazide works

Losartan + Amlodipine + Hydrochlorothiazide is a combination of three medicines: Losartan , Amlodipine and Hydrochlorothiazide. Losartan is an angiotensin receptor blocker (ARB) and Amlodipine is a calcium channel blocker (CCB). They work by widening and relaxing the blood vessels, thereby lowering blood pressure. Hydrochlorothiazide is a diuretic which removes extra water and certain electrolytes from the body through urine. Over time it also works by relaxing blood vessels and improving blood flow.

Common side effects of Losartan + Amlodipine + Hydrochlorothiazide

Ankle swelling, Headache, Dizziness, Tiredness, Palpitations, Sleepiness, Increased blood uric acid, Glucose intolerance, Taste change, Flushing (sense of warmth in the face, ears, neck and trunk), Upset stomach, Altered blood lipid level
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Expert advice for Losartan + Amlodipine + Hydrochlorothiazide

  • You have been prescribed Losartan + Amlodipine + Hydrochlorothiazide for the treatment of high blood pressure.
  • Lowering high blood pressure helps prevent strokes and heart attacks.
  • It may cause dizziness. Get up slowly when rising from a sitting or lying position.
  • Losartan + Amlodipine + Hydrochlorothiazide may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, muscle weakness or very dry mouth.
  • Use of Losartan + Amlodipine + Hydrochlorothiazide during pregnancy or breastfeeding is unsafe.