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Pulseless ventricular fibrillation or ventricular tachycardia, epidural anaesthesia, spinal anaesthesia, surface anaesthesia, percutaneous infiltration anaesthesia, peripheral nerve block.

How it works

Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses thereby effecting local anesthetic action. Lidocaine alters signal conduction in neurons by blocking the fast voltage gated sodium (Na+) channels in the neuronal cell membrane that are responsible for signal propagation.

Common side effects

Convulsion, Confusion, Drowsiness, Paresthesia (tingling or pricking sensation), Dizziness, Respiratory depression


Content on this page was last updated on 17 May, 2016, by Dr. Varun Gupta (MD Pharmacology)