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Irbesartan + Chlorthalidone + Amlodipine

Written By Dr. Subita AlaghReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:37 AM (UTC)

Irbesartan + Chlorthalidone + Amlodipine Uses

Irbesartan+Chlorthalidone+Amlodipine is used in the treatment of Hypertension (high blood pressure).

How Irbesartan + Chlorthalidone + Amlodipine works

Irbesartan + Chlorthalidone + Amlodipine is a combination of three medicines : Irbesartan, Chlorthalidone, and Amlodipine. Irbesartan is an angiotensin receptor blocker (ARB). It relaxes the blood vessel by blocking the action of a chemical that usually makes blood vessels tighter. This lowers the blood pressure, allowing the blood to flow more smoothly to different organs and the heart to pump more efficiently. Chlorthalidone is a diuretic which lowers blood pressure by removing extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow. Amlodipine is a calcium channel blocker. In high blood pressure, it normalizes the blood pressure by relaxing the blood vessels to reduce the pressure on them, thereby improving the blood flow in the body. The enhanced blood flow in the body, further relaxes the heart muscles by reducing the workload on the heart. It also improves the oxygen flow in the body, thereby, preventing any heart-related chest pain.
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