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    Hydroxyurea

    Information about Hydroxyurea

    Hydroxyurea uses

    Hydroxyurea is used in the treatment of sickle cell anemia.

    How hydroxyurea works

    Hydroxycarbamide causes inhibition of DNA synthesis during the S-phase of cell division by acting as a ribonucleotide reductase inhibitor resulting to cell death. It is S-phase specific.

    Common side effects of hydroxyurea

    Megaloblastic anemia, Decreased white blood cell count (neutrophils), Oligospermia (low sperm count), Azoospermia (absence of sperms)

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    Content on this page was last updated on 18 September, 2017, by Dr. Varun Gupta (MD Pharmacology)