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Hydroxyurea

INFORMATION

Uses

Hydroxyurea is used in the treatment of sickle cell anemia.

How it works

Hydroxycarbamide causes inhibition of DNA synthesis during the S-phase of cell division by acting as a ribonucleotide reductase inhibitor resulting to cell death. It is S-phase specific.

Common side effects

Vomiting, Nausea, Shortness of breath, Numbness, Pale colored skin, Frequent urge to urinate, Difficulty in urination, Acne-like rash, Blisters on skin, Burning sensation, Tingling sensation, Itching, Constipation, Darkening of skin, Fatigue, Hair loss, Dizziness, Headache, Influenza like symptoms, Loss of appetite, Skin rash, Skin redness, Sore mouth, Sore throat, Stomach pain / epigastric pain, Tachycardia, Weight gain, Yellow discoloration of skin, Yellow discoloration of eye

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Content on this page was last updated on 11 November, 2016, by Dr. Varun Gupta (MD Pharmacology)