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Gestodene is used in contraception

How it works

Gestodene belongs to class of medications called oral progesterone contraceptives. It works by changing the lining of the uterus thereby making it difficult for an egg (female gamete) to develop and it also prevents release of eggs from the ovary (female gonads). Further it increases the thickness of cervical fluid (at the opening of uterus) which prevents the sperms (male gamete) from reaching an egg.

Common side effects

Adrenal insufficiency, Rash, Vaginal discharge, Headache, Dizziness, Back pain, Increased appetite, Decreased libido, Pain in extremity, Abdominal distension, Cushing syndrome, Sleepiness, Vomiting, Nausea, Edema, Abdominal pain, Lower abdominal pain, Breast pain, Hair loss, Fatigue, Acne, Hot flushes, Thrombophlebitis, Diarrhoea, Irregular menstrual cycle, Depression, Cushingoid syndrome, Increased blood pressure, Mood changes, Nervousness, Constipation, Increased glucose level in blood, Breathing difficulty

Available Medicine

No medicine available

Expert advice

  • Caution should be exercised before taking gestodene if you are obese, have high blood lipids, heart problems, kidney/liver problem, sickle cell anemia (abnormal red blood cells) or varicose veins (dilated veins in legs).
  • You should undergo regular cervical smear tests while on gestodene therapy as it increases your risk of cancer of the cervix.
  • You should check your breasts and nipples regularly and report any abnormal changes seen during breast cancer, such as lumps or dimpling of the skin. 
  • Gestodene can affect the results of some tests. Inform your doctor that you are taking gestodene.
  • Gestodene may increase your risk of having a blood clot in the veins and arteries, especially in the first year or when restarting following a break of 4 or more weeks. 
  • Inform your doctor if you are planning to undergo a surgery as gestodene may cause complications in the surgical procedure due to blood clot formation.
  • Tell your doctor if you have family history of blood clots, had recent surgery or trauma, have metabolic problems, are above 35 years of age, immobile for a long period, have given birth in last 6-8 weeks.
  • Consult your doctor before taking gestodene if you have vaginal bleeding due to unknown reason.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently asked questions


Q. What is gestodene, ethinylestradiol?
Both gestodene and ethinylestradiol are oral contraceptive pills.

Content on this page was last updated on 10 February, 2017, by Dr. Varun Gupta (MD Pharmacology)