Exenatide is used in the treatment of type 2 diabetes
How it works
Exenatide works by stimulating the pancreas to secrete more insulin when blood sugar levels are high. It also lowers the sugar hormone (glucagon) and slows the emptying of the stomach. Insulin lowers blood sugar from the blood into other body tissues where it is used for energy.
Common side effects
Headache, Nausea, Vomiting, Diarrhoea, Hypoglycaemia (Low blood sugar level) in combination with insulin or sulphonylurea
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- The dose can be administered at any time of day, with or without meals.
- It is injected under the skin (subcutaneous injection) of your stomach area (abdomen) or upper leg (thigh). If the injection is given by someone else, they may inject in your upper arm.
- Do not change the dose without consulting your doctor.
- Report to your doctor if you experience abdominal pain while taking this medicines.
- If a dose is missed, it should be taken as soon as possible if there are at least 3 days (72 hours) until the next scheduled dose. If less than 3 days remain before the next scheduled dose, the missed dose should be skipped and the next dose should be administered on the regularly scheduled day. In each case, patients can then resume their regular once weekly dosing schedule.
Frequently asked questions
Q. Is exenatide insulin?
Exenatide is not insulin. Exenatide is synthetic version of exendin-4 (a hormone) and works by stimulating pancreatic beta-cells to secrete insulin when blood sugar levels are high
Q. Is exenatide safe?
Exenatide is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Q. Does exenatide cause hypoglycemia?
Exenatide itself does not cause hypoglycemia (low blood sugar), but may cause low blood sugar when taken with other antidiabetic medicines
Q. How does exenatide cause pancreatitis?
Few patients can suffer from pancreatitis
Q. How is exenatide administered?
Exenatide is administered as 2 mcg subcutaneous injection once weekly
Q. How is exenatide metabolized?
It is not metabolized in body and excreted unchanged in urine.