Eribulin Mesylate

Information about Eribulin Mesylate

Eribulin Mesylate Uses

Eribulin Mesylate is used in the treatment of metastatic breast cancer. It is used to treat adults with breast cancer that has spread to other parts of the body, and who have already received other anticancer medicines after the cancer has spread.

How Eribulin Mesylate works

Eribulin Mesylate is an anticancer medication. It works by interfering with the microtubule structures which help the cancer cells to divide and multiply. This blocks the growth cycle (cell cycle) of cancer cells and eventually kills them.

Common side effects of Eribulin Mesylate

Anemia (low number of red blood cells), Weakness, Hair loss, Nausea, Constipation, Decreased white blood cell count, Fatigue, Peripheral neuropathy (tingling and numbness of feet and hand)
CONTENT DETAILS
Written By
Dr. Radhika Dua
MDS, BDS
Reviewed By
Dr. Shilpa Garcha
MD (Pharmacology), MBBS
Last updated
18 Mar 2020 | 05:14 AM (UTC)

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Available Medicine for Eribulin Mesylate

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EpbrivHetero Healthcare Limited
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EbunatNatco Pharma Ltd
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EvairaZydus Cadila
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HalavenEisai Pharmaceuticals India Pvt Ltd
₹318851 variant(s)

Expert advice for Eribulin Mesylate

  • Eribulin Mesylate helps treat breast cancer that has spread to other areas of the body.
  • It is given by an injection into a vein (intravenously).
  • It may cause dizziness and tiredness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for three months after you stop taking it.
  • Your doctor may get regular blood tests done to monitor your blood cells and electrolyte levels during treatment with this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea while taking this medicine.
  • It may cause numbness, tingling or pricking sensations in your hands and feet. Inform your doctor if this bothers you.

Frequently asked questions for Eribulin Mesylate

Eribulin Mesylate

Q. Is hair loss caused by Eribulin Mesylate irreversible?

Hair loss is a common side effect of Eribulin Mesylate. It could be reversible but the severity of hair loss varies from person to person. Consult your doctor if you have any concerns regarding hair loss.

Q. How long can I stay on Eribulin Mesylate?

Eribulin Mesylate is usually given on Days 1 and 8 of each recommended 21-day cycle. The duration of treatment varies from person to person. The number of cycles required for effective treatment will be decided by your doctor. Depending on the results of your blood tests, the doctor may need to delay administration of the medicine until the blood tests return to normal. If required, the doctor may also decide to reduce the dose you are given.

Q. How is Eribulin Mesylate Mesylate administered?

Eribulin Mesylate will be given to you by a doctor or healthcare professional as an injection into a vein, over a period of 2 to 5 minutes. The dose required will be decided based on your body surface area (expressed in square metres, or m2) which is calculated from your weight and height. The doctor may adjust the usual dose based on your blood test results or other factors. To ensure that the whole dose of Eribulin Mesylate is given, it is recommended that a saline solution is flushed into the vein after Eribulin Mesylate is given.

Q. What are the serious side effects of Eribulin Mesylate?

Eribulin Mesylate can cause serious side effects which include low white blood cell count (neutropenia). This can lead to serious infections that could lead to death. It can also cause numbness, tingling, or pain in your hands or feet (peripheral neuropathy). Peripheral neuropathy is common with Eribulin Mesylate and sometimes can be severe. It can cause harm to the baby when administered to a pregnant woman.

Q. When can I plan a pregnancy if I am using Eribulin Mesylate?

Women of childbearing age should use effective contraception during and up to 3 months after treatment with Eribulin Mesylate.It may cause serious birth defects and should not be used if you are pregnant unless it is thought clearly necessary after carefully considering all the risk to you and the baby.

Q. What precautions should be followed while handling Eribulin Mesylate?

Eribulin Mesylate should be handled carefully. Avoid any contact with skin, eyes, mouth and insides of nose. It is recommended to use gloves, goggles, and protective clothing while handling the medicine. If the skin comes into contact with the solution, it should be washed immediately and thoroughly with soap and water. Similarly, if your eyes, mouth or nose come in contact with Eribulin Mesylate, flush the area thoroughly with water. Pregnant staff should not handle Eribulin Mesylate.

Q. In which solution should Eribulin Mesylate injection be diluted?

Eribulin Mesylate may be diluted in up to 100 ml of sodium chloride 9 mg/ml (0.9%) solution and not in 5% dextrose. It should be given under the supervision of a physician experienced in giving cancer chemotherapy and should be administered by a health care professional only.

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