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Eltrombopag is used to treat a blood disorder called  chronic immune thrombocytopenic purpura (a long-standing condition where an individual’s immune system destroys the platelets [cells responsible for blood clotting] resulting in easy bruising and bleeding). It is also used in adult patients with hepatitis C virus infection with decreased platelets  who require interferon-based treatment, and patients with severe aplastic anemia (deficiency of all types of blood cells caused by failure of bone marrow function).

How it works

Eltrombopag belongs to class of drugs called antihemorrhagics. It works by activating the production and proliferation of platelets from bone marrow.

Common side effects

Numbness of extremity, Frequent urge to urinate, Difficulty in urination, Back pain, Body ache, Cough, Fatigue, Weakness, Hair loss, Headache, Influenza like symptoms, Insomnia, Loss of appetite, Abnormally heavy bleeding at menstruation, Mouth swelling, Muscle cramp, Muscle pain, Running nose, Nasal congestion, Skin rash, Sore throat, Throat swelling, Chills, Fever


Expert advice

  • It is not advisable to administer eltrombopag to children and adolescents below 18 years.
  • Tell your doctor before taking eltrombopag if you have liver disease, risk of forming blood clots in your veins or arteries (due to old age, overweight, recent surgery causing a long-standing bed-ridden state, cancer, treatment with oral contraceptive pills, smoking), or have a family history of forming abnormal blood clots.
  • Exercise caution if you have myelodysplastic syndrome (condition wherein blood cells in the bone marrow do not mature or become healthy) as eltrombopag might worsen this condition.
  • You may be regularly examined with blood tests to monitor the blood cell counts (red blood cells, white blood cells and platelets), liver function, bone marrow function, heart, and gut bleeding when receiving treatment with eltrombopag.
  • Do not drive or use machines after taking eltrombopag as it can impair co-ordination.
  • Do not consume this drug if you are allergic to eltrombopag or any of its ingredients.
  • Tell your doctor if you are pregnant or planning to become pregnant or are breastfeeding.

Frequently asked questions


Q. Is eltrombopag available in India?
Yes, eltrombopag is available in India.
Q. Is eltrombopag approved by US FDA and available in India?
Yes, eltrombopag is approved by US FDA and it is available in India. 

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)