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Eliglustat

INFORMATION ABOUT ELIGLUSTAT

Eliglustat Uses

Eliglustat is used in the treatment of Gaucher disease.

How Eliglustat works

Eliglustat works by blocking an enzyme called glucosylceramide synthase, which is responsible for making fatty substances that build up in Gaucher disease. It lowers their production, prevents excess storage in organs like the liver, spleen, and bone marrow, helping to reduce symptoms and organ damage.

Common side effects of Eliglustat

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common
Fatigue, Headache, Nausea, Diarrhea, Back pain, Pain in extremities, Upper abdominal pain
CONTENT DETAILS
Last updated
09 Sep 2025 | 11:42 AM (UTC)
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Expert advice for Eliglustat

  • Do not skip doses. Long gaps may reduce its benefit and allow disease progression.
  • Inform your doctor if you have liver, kidney, or heart issues before starting treatment of Eliglustat.
  • Certain genetic tests (CYP2D6 status) may be done to decide the right dose of Eliglustat for you.
  • Regular monitoring through blood tests and doctor visits is important to track the response.
  • Avoid herbal products or over-the-counter medicines without consulting your doctor, as they may interfere with Eliglustat.

Frequently asked questions for Eliglustat

It should be taken by mouth at the same time each day, swallowed whole with water. Do not crush or chew the Eliglustat.
No. Stopping without medical advice may allow Gaucher symptoms to return or worsen. Always follow your doctor’s instructions.
Take it as soon as you remember. If it is almost time for the next dose, skip the missed one. Do not double up.
Some medicines, especially those affecting the liver or heart rhythm, may interact. Always tell your doctor about all drugs you are using.