Information about Dulaglutide

Dulaglutide Uses

Dulaglutide is used in the treatment of type 2 diabetes mellitus. It can be used as a monotherapy (single therapy) when diet and exercise alone do not provide proper blood sugar control in patients for whom metformin is considered inappropriate. It can also be used as an add-on therapy with other glucose-lowering medicines if needed.

How Dulaglutide works

Dulaglutide is an antidiabetic medication. It works by increasing the release of insulin from the pancreas, decreases hormones that raise blood sugar levels, slows down digestion, and reduces appetite.

Common side effects of Dulaglutide

Nausea, Vomiting, Diarrhea, Decreased appetite, Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea
CONTENT DETAILS
Written By
MMST, MBBS
Reviewed By
MD (Pharmacology), MBBS
Last updated:
18 Feb 2020 | 11:54 AM (UTC)
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Available Medicine for Dulaglutide

AplevantLupin Ltd
49982 variant(s)
TrulicityEli Lilly and Company India Pvt Ltd
49982 variant(s)

Expert advice for Dulaglutide

  • Dulaglutide should be injected under the skin of your abdomen or thigh once a week. Do not administer intravenously or intramuscularly.
  • You can inject into the same body area each week, but try not to use the exact same spot.
  • Store the pen in the refrigerator. When refrigeration is not possible, you can also keep your pen at room temperature (less than 30°C) for up to 2 weeks. Do not freeze it.
  • Do not use Dulaglutide if particles appear or if the solution is cloudy and/or discolored.
  • Dulaglutide may cause nausea, vomiting, diarrhea, or stomach pain, which may get better with time. Eat smaller meals, limit fatty food intake and inform your doctor if it does not go away.

Frequently asked questions for Dulaglutide

Dulaglutide

Q. Is Dulaglutide an insulin?

No, Dulaglutide is not an insulin. It is a medicine used to lower blood sugar (glucose) levels in adults with type 2 diabetes mellitus. In type 2 diabetes there is a deficiency of insulin, and the insulin that your body produces does not work as well as it should. Dulaglutide acts on the pancreas to increase insulin release, suppress glucagon secretion and decrease glucose production from the liver. It also slows down the emptying of the stomach.

Q. How does Dulaglutide work for weight loss?

Dulaglutide is used in type 2 diabetes mellitus. It improves blood sugar control and slows down the digestion. This brings a feeling of fullness and satiety due to which the food intake by the patient decreases. As a result, the patient eats less which further helps in weight loss.

Q. How is Dulaglutide administered?

Dulaglutide is injected under the skin (subcutaneously) of your stomach, thigh, or upper arm. It should not be injected into a muscle or vein. You can use the same area of your body each week to take the injection, but make sure that a different injection site is used within that area. Use Dulaglutide as advised by your doctor. You can take it with or without food. If you are on insulin as well, do not mix insulin and Dulaglutide in the same syringe. It is also recommended to check your blood sugar levels regularly.

Q. How to store Dulaglutide?

Dulaglutide should be refrigerated at 2°C - 8°C, but do not freeze it. Store Dulaglutide in the original packaging in order to protect from light. Keep the medicine out of the reach of children. Do not use the medicine if you notice that the pen is damaged or the medicine has become cloudy/discolored or has lumps in it.

Q. Are there any potential risks of using Dulaglutide?

Apart from the usual side effects of the medicine, Dulaglutide has been found to cause Medullary Thyroid Carcinoma, a type of cancer of thyroid gland. Its use may also increase the risk of inflammation of pancreas commonly known as pancreatitis which is a serious and painful condition. Discontinue the medicine and contact your doctor immediately if you suspect any signs or symptoms of thyroid problems (lump in throat, hoarseness and difficulty in speaking) or pancreatitis (stomach ache radiating to the back, upper abdominal pain, fever, nausea and vomiting).

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