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Doxazosin is used to treat signs and symptoms of benign prostatic hyperplasia (BHP, also known as enlarged prostate) such as urinary outflow obstruction (characterized by hesitation, intermittency, dribbling, weak urinary stream, and incomplete emptying of the bladder) and obstructive and irritative symptoms (nocturia, daytime frequency, urgency, burning). Doxazosin is also used alone or in combination with other medications for the treatment of hypertension (high blood pressure).

How it works

Doxazosin belongs to class of medications called alpha-blockers. Doxazosin causes relaxation of the smooth muscle tone in the prostate and bladder neck, hence the urine is passed easily in patients with enlarged prostrate. Further, doxazosin relaxes the blood vessels, thereby lowering the high blood pressure.

Common side effects

Abdominal pain, Decreased blood pressure, Diarrhoea, Fatigue, Dizziness, Shortness of breath, Headache, Increase in body weight, Muscle pain, Joint pain, Nausea, Running nose, Weakness


Expert advice

  • You may experience syncope (temporary loss of consciousness caused by a fall in blood pressure) especially in the upright position, along with other postural symptoms such as dizziness after the first dose. Do not panic, you should sit or lie down until you feel better.
  • Inform your doctor that you are on doxazosin therapy, if you are to undergo an eye surgery for cataract so as to avoid the complications during cataract surgery.
  • Do not drive or operate machinery as doxazosin may make you drowsy or dizzy.
  • Take screening test for the presence of prostate cancer prior to treatment and at regular intervals afterwards.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently asked questions


 Q. Is doxazosin a beta blocker or an alpha blocker?
Doxazosin belongs to class of medications called alpha-receptor blockers or alpha-blockers.
Q. Is doxazosin or doxazosin mesylate safe?
Doxazosinare or doxazosin mesylate are safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is doxazosin a statin or a blood thinner (thin the blood)?
Doxazosin is neither a statin nor a blood thinner.
Q. Is doxazosin a diuretic?
No, doxazosin is not a diuretic, it antagonizes the alpha receptors causing relaxation of the smooth muscle tone in the prostate and bladder neck, hence the urine is passed easily in patients with enlarged prostrate.
Q. Is doxazosin a narcotic?
No, doxazosin is not a narcotic
Q. Does doxazosin lower heart rate?
No, doxazosin is not known to reduce heart rate. Increase in heart rate or irregular heart rate is a common adverse event reported for doxazosin.
Q. Does doxazosin cause hair loss or weight gain?
Hair loss and weight gain are uncommon side effects of doxazosin therapy.
Q. Does doxazosin cause erectile dysfunction?
No, doxazosin is not known to cause erectile dysfunction
Q. Does doxazosin cause retrograde ejaculation?
Doxazosin may rarely cause retrograde ejaculation.
Q. Does doxazosin cause coughing?
Yes, coughing is a common side effect of doxazosin.
Q. Does doxazosin make you tired?
Yes, doxazosin may make you feel tired and sleepy.
Q. Can I take doxazosin with Viagra (sildenafil) or Cialis (tadalafil)?
Please follow your doctor’s advice before taking these medications with doxazosin. As combining Viagra (sildenafil) or Cialis (tadalafil) with doxazosin can lower your blood pressure and increase the risk of dizziness, lightheadedness, fainting, flushing, headache, and nasal congestion.
Q. Can I take saw palmetto with doxazosin?
There are no known interactions between saw palmetto and doxazosin.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)