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Dihydralazine is used with or without other medications for treating moderate to severe high blood pressure (hypertension). It is also used to manage congestive heart failure along with other medications.

How it works

Dihydralazine belongs to class of anti-hypertensive medications called thiazide derivatives. It works as a vasodilator and relaxes and dilates (opens) the blood vessels in the body, allowing blood to flow through the vessels more easily thereby lowering blood pressure.

Common side effects

Nausea, Palpitations, Back pain, Jaw pain, Chest discomfort, Chest pain, Chest tightness, Shortness of breath, Headache, Altered heart rate, Increased sweating


Expert advice

  • Stop taking dihydralazine if you develop serious or life-threatening allergic reaction. 
  • Do consult your doctor if you have had a heart attack, pain in the chest (angina), narrowing of blood vessels of the brain (cerebrovascular disease), serious liver or kidney disease.
  • Do not stop taking dihydralazine unless advised by a doctor.
  • Dihydralazine may make you drowsy, dizzy, or confused. Do not drive or operate machinery until you know how this medication affects you.
  • Tell your doctor if you are pregnant or planning to become pregnant or are breastfeeding.
  • With prolonged use of dihydralazine in large doses, a condition resembling autoimmune disease affecting skin, joints, kidneys, brain, and other organs (systemic lupus erythematosus) may develop.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)