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Dexchlorpheniramine is used to relieve symptoms of sinus congestion, running nose, watery eyes, itching of the nose and throat, and sneezing due to upper respiratory infections (eg. colds), allergies due to food and insect bites and hay fever.

How it works

Dexchlorpheniramine belongs to class of medications called antihistamines. It acts by blocking a natural chemical (histamine) that your body makes during an allergic reaction.

Common side effects

Nausea, Rash, Blurred vision, Chest tightness, Chills, Constipation, Coordination impaired, Dizziness, Dry nose, Difficulty in urination, Early menstrual periods, Headache, Loss of appetite, Nasal congestion, Sedation, Sleepiness, Frequent urge to urinate, Vertigo, Wheezing, Dry mouth, Fatigue


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Expert advice

  • Do not dexchlorpheniramine, if you are allergic (hypersensitive) to dexchlorpheniramine or any of the other ingredients of dexchlorpheniramine tablet.
  • Consult your doctor before taking dexchlorpheniramine if you have fits (epilepsy); enlarged prostate; increased pressure in the eye that cause visual problems (glaucoma); heart disease; liver disease; lung disease; or an overactive thyroid gland.
  • Do not drive or operate machinery after taking dexchlorpheniramine because you may feel sleepy.

Frequently asked questions


Q. Does dexchlorpheniramine or dexchlorpheniramine maleate cause increase in blood pressure/ drowsy/non drowsy/sedating/get you high/keep you awake/sleepiness/make you tired/weight gain?
Dexchlorpheniramine causing these side effects is common or rare. Always consult your doctor if you experience any of these side effects.
Q. Is dexchlorpheniramine like Benadryl?
No, dexchlorpheniramine is different from Benadryl.
Q. Is dexchlorpheniramine prescription?
Yes, it is available with doctor’s prescription only.
Q. Can I take dexchlorpheniramine with Panadol/cetirizine/Zyrtec/Allegra/ warfarin/diphenhydramine/ibuprofen/Claritin/guaifenesin/Benadryl?
Yes, but taking other medicines may alter the effects of dexchlorpheniramine. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)