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Desoximetasone is used in the relief of dermatoses (non-inflammatory skin lesions) especially plaque psoriasis.

How it works

Desoximetasone is a potent corticosteroid that acts by reducing the activation of inflammatory cells and formation of chemicals responsible for the inflammatory process of dermatoses.

Common side effects

Perioral skin inflammation, Itchy rash, Acneiform eruptions, Burning sensation, Inflammation of hair follicles, Increased hair growth, Irritation, Itching, Lightening of skin color, Miliaria (blocked sweat ducts), Secondary infections, Stretch marks


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Expert advice

  • Desoximetasone is for external use only. Avoid contact/ use on eyes, face, axilla or groin.
  • Treated skin area should not be bandaged or otherwise covered unless advised by your doctor.
  • Excess absorption of desoximetasone in skin may cause Cushing’s syndrome (abdominal obesity, accumulation of fat over nape of neck, loss of fat over arms and legs, thinning and easy bruisability of skin), increased blood sugar, and excretion of glucose in urine in some patients.
  • Treatment beyond 4 weeks is not recommended.
  • Prolonged or excessive use may lead to suppression of steroid production within the body, with serious consequences once desoximetasone use is stopped. You should therefore be periodically evaluated.
  • When given to the patients younger than 18 years old, desoximetasone may lead to retarded growth.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently asked questions


Q. Is desoximetasone a steroid?
Yes, desoximetasone is a corticosteroid.
Q. Is desoximetasone cream used for acne, eczema, poison ivy, ringworm or scabies?
Desoximetasone can be used to relieve itching and redness associated with eczema, poison ivy and ringworm. It is however not recommended for use in acne or scabies.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)