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Daptomycin

INFORMATION

Uses

Daptomycin is used in the treatment of serious bacterial infections.

How it works

Daptomycin belongs to a class of antibiotics called the cyclic lipopeptides. It is an antibacterial agent that works by killing the bacteria or stopping their growth.

Common side effects

Nausea, Liver enzyme increased, Increased creatine phosphokinase level in blood, Abdominal pain, Altered sleep, Anemia, Anxiety, Fungal infection, Constipation, Increased blood pressure, Decreased blood pressure, Diarrhoea, Dizziness, Fever, Flatulence, Headache, Rash, Itching, Skin redness, Abdominal bloating, Swelling of abdomen, Urinary tract infection, Vomiting, Weakness

AVAILABLE MEDICINE

Expert advice

  • Do not skip any dose or discontinue this medicine, as it may increase your chances of developing drug resistance.
  • Tell your doctor if you experience symptoms of serious allergic reaction, such as wheezing, difficulty breathing, swelling of the face, neck and throat, rashes and hives, fever; any unusual tingling or numbness of the hands or feet, loss of feeling or difficulties with movements; bloody or watery diarrhea; signs of eosinophilic pneumonia such as new or worsening fever, cough or difficulty breathing.
  • This medicine can cause unusual results with certain medical tests (especially blood clotting test).
  • Your doctor will perform blood tests to monitor the health of your muscles both before you start treatment and frequently during treatment with daptomycin.

Frequently asked questions

Daptomycin

Q.Is daptomycin a penicillin/ nephrotoxic/ bactericidal/ a vesicant/an aminoglycoside/ vancomycin/ dialyzable/ bacteriostatic/ a macrolide/ latex free?
Daptomycin is not a penicillin, vancomycin, aminoglycoside, macrolide. It is a bactericidal not bacteriostatic agent. It shows slight nephrotoxicity. It is a vesicant and is latex free

Q.Does daptomycin cover methicillin- resistant staphylococcus aureus (MRSA)/ pseudomonas/ streptococcus/anaerobes/ klebsiella?
Daptomycin exhibits rapid, bactericidal activity against Gram-positive organisms including Staphylococcus, Streptococcus, Enterococcus and isolates resistant to methicillin (MRSA), vancomycin, and linezolid

Q.Does daptomycin cross the blood-brain barrier/penetrate cerebrospinal fluid (CSF)?
Daptomycin does not cross the blood-brain barrier or penetrate CSF

Q.Does daptomycin cause renal failure?
Daptomycin may result in renal toxicity in some cases

Q.Does daptomycin dialyzed out?
Yes. Daptomycin can be dialyzed out.


Content on this page was last updated on 16 November, 2016, by Dr. Varun Gupta (MD Pharmacology)