Dalfampridine
Written By Dr. Anuj Saini
Reviewed By Dr. Rajeev SharmaLast updated 25 Nov 2025 | 09:34 AM (UTC)
Dalfampridine Uses
Dalfampridine is used in the treatment of multiple sclerosis (MS). It helps to improve walking ability and walking speed in people with multiple sclerosis.
How Dalfampridine works
Dalfampridine is a potassium channel blocker. It works by strengthening the communication between nerves and muscles. This results in improved muscle activity – in this case, walking – in people with multiple sclerosis.
Common side effects of Dalfampridine
Influenza, Viral infection, Anxiety, Vertigo, Palpitations, Breathlessness, Vomiting
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Expert advice for Dalfampridine
- Dalfampridine helps improve walking in adults with multiple sclerosis.
- It may take 2-6 weeks for the medicine to start working. Keep taking it as prescribed.
- Do not chew, cut, or crush the tablet as that may results in releasing too much medicine in your body at once.
- Inform your doctor if you have a history of seizures or kidney problems.
Frequently asked questions for Dalfampridine
Dalfampridine may take a few weeks to improve the condition. The effect of the medicine on a particular patient varies according to the severity of the condition and response of the patient. Hence, during treatment with Dalfampridine, patient should be monitored on a weekly basis. Do consult your doctor and follow the instructions as given by your doctor.
Dalfampridine is used in the therapy of multiple sclerosis. It acts by increasing the conduction in the damaged neurons by blocking potassium channels. The effect with this medicine can be seen with an increase in walking speed in treated patients.
Patients with kidney problems, allergic to Dalfampridine, or who ever had an episode of seizure should not take Dalfampridine. You should consult your doctor before you start taking this medication.
Usually this medication is to be stored at 15ºC to 30ºC. The medicine should be stored in the original packaging in order to protect from light and moisture. Do not use the medicine after its expiry date. Keep the medicine out of the reach of children.
Take the medicine exactly as prescribed by the doctor. Usually, it is advised to take one tablet twice daily with or without food about 12 hours apart. Take the medicine whole, do not break, crush, or chew.