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Clotrimazole + Clobetasol + Neomycin

Written By Dr. Sakshi JainReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:37 AM (UTC)

Clotrimazole + Clobetasol + Neomycin Uses

Clotrimazole+Clobetasol+Neomycin is used in the treatment of skin infections.

How Clotrimazole + Clobetasol + Neomycin works

Clotrimazole + Clobetasol + Neomycin is a combination of three medicines: Clotrimazole , Clobetasol and Neomycin, which treats skin infections. Clotrimazole is an antifungal which stops the growth of fungi by preventing them from forming their own protective covering. Clobetasol is a steroid medicine. It blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy. Neomycin is an antibiotic. It stops bacterial growth by preventing the synthesis of essential proteins required by the bacteria to carry out vital functions.

Common side effects of Clotrimazole + Clobetasol + Neomycin

Application site reactions (burning, irritation, itching and redness)
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Expert advice for Clotrimazole + Clobetasol + Neomycin

  • Clotrimazole + Clobetasol + Neomycin must be applied as a thin layer on the affected area as prescribed by your doctor.
  • Do not use this medicine more often or for longer than advised by your doctor.
  • Before each application, wash the affected area with soap and water and dry well. 
  • Avoid getting it in the eyes, mouth or nose. Rinse with cold water if you accidentally get it in these areas.
  • Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
  • Inform your doctor if the treated skin area does not improve after 2-4 weeks of treatment.

Frequently asked questions for Clotrimazole + Clobetasol + Neomycin

No, do not stop using Clotrimazole+Clobetasol+Neomycin and complete the full course of treatment, even if you feel better. Your symptoms may improve before the infection is completely cured.
Clotrimazole+Clobetasol+Neomycin should not be used on the face and any contact with the eyes should be avoided. Do not apply a bandage or dressing on the area being treated, as this will increase absorption of the medicine and increase the risk of side effects. This medicine should only be used for the condition it is prescribed for. Do not use it for any other condition without consulting your doctor. Do not give it to other people even if their condition appears to be the same.
Clotrimazole+Clobetasol+Neomycin should be used as advised by the doctor or as per the instructions on the label of the medicine. Apply a thin layer of Clotrimazole+Clobetasol+Neomycin to cover the affected areas. The dose would depend on the condition for which it is prescribed. Wash your hands after using Clotrimazole+Clobetasol+Neomycin unless it is used for treating infection of the hands. Avoid contact with the eyes.
Use of Clotrimazole+Clobetasol+Neomycin is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine. Avoid its use in case of any fungal infections (ringworm or athlete's foot), viral infections (herpes or chickenpox) or for treatment of acne or rosacea. Consult your doctor before using it for any condition.
Keep this medicine in the packet or the container it came in. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.