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Calcium Leucovorin

Written By Dr. Lipika KhuranaReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:34 AM (UTC)

Calcium Leucovorin Uses

Calcium Leucovorin is used to prevent harmful effects of methotrexate, common cold and cough with fever and headache. It is also used to treat overdose of methotrexate.
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Expert advice for Calcium Leucovorin

  • You have been prescribed Calcium Leucovorin to reduce the side effects of the medicine methotrexate.
  • Take it 24 hours after taking methotrexate. If taken at the same time, it may counteract the effect of methotrexate.
  • Inform your doctor if you are also taking certain medications such as phenytoin for your seizures as Calcium Leucovorin may counteract the antiepileptic effects.
  • You have been prescribed Calcium Leucovorin to reduce the side effects of the medicine methotrexate.
  • Take it 24 hours after taking methotrexate. If taken at the same time, it may counteract the effect of methotrexate.
  • Inform your doctor if you are also taking certain medications such as phenytoin for your seizures as Calcium Leucovorin may counteract the antiepileptic effects.