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Calcium Folinate



Calcium Folinate is used in the treatment of ovarian cancer, blood cancer, hemorrhagic cystitis and methotrexate toxicity

How it works

Calcium folinate enters the cells as 5-methyl tetrahydrofolate and supplies the cofactor blocked by methotrexate. It stabilises the binding of 5-dUMP and thrymidylate synthetase, enhances flourouracil activity and neutralises the effects of folic acid antagonists such as methotrexate but increases those of 5-fluorouracil.

Common side effects

Nausea, Vomiting, Diarrhoea, Mucosal inflammation

Available Medicine

  • ₹98 to ₹250
    Dabur India Ltd
    2 variant(s)
  • ₹121 to ₹450
    Biochem Pharmaceutical Industries
    2 variant(s)
  • ₹297
    Biochem Pharmaceutical Industries
    1 variant(s)
  • ₹95 to ₹267
    Celon Laboratories Ltd
    2 variant(s)
  • ₹100
    Samarth Life Sciences Pvt Ltd
    1 variant(s)
  • ₹95 to ₹266
    Zydus Cadila
    2 variant(s)
  • ₹325
    Alkem Laboratories Ltd
    1 variant(s)
  • ₹96 to ₹289
    Parenteral Drugs India Ltd
    2 variant(s)

Content on this page was last updated on 16 February, 2017, by Dr. Varun Gupta (MD Pharmacology)