Brigatinib
Written By Dr. Sakshi Jain
Reviewed By Dr. Rajeev SharmaLast updated 31 Jul 2026 | 10:43 AM (UTC)
Brigatinib Uses
Brigatinib is used in the treatment of non-small cell lung cancer.
How Brigatinib works
Brigatinib works by blocking an abnormal protein called anaplastic lymphoma kinase (ALK) that helps certain lung cancer cells grow and spread. By blocking this protein, Brigatinib slows the growth of cancer cells and helps control disease progression.
Common side effects of Brigatinib
Diarrhea, Fatigue, Nausea, Rash, Cough, Muscle pain, Headache, High blood pressure, Vomiting, Breathlessness
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Expert advice for Brigatinib
- Attend all scheduled follow-up visits and blood tests so your doctor can monitor your blood pressure, blood sugar, liver function, muscle enzymes, and pancreatic enzymes during treatment.
- Be especially alert for new or worsening breathing problems during the first week of treatment and report them immediately.
- Tell your doctor promptly if you notice blurred vision, double vision, or any other changes in your eyesight, as an eye examination may be needed.
- Protect your skin from sunlight by wearing protective clothing and applying sunscreen during treatment and for at least 5 days after your last dose.
- Inform your doctor about all medicines, vitamins, herbal products, and dietary supplements before starting or stopping any medicine to help avoid drug interactions.
Frequently asked questions for Brigatinib
Yes. Brigatinib can be taken with or without food. Swallow the tablet whole with water and do not crush or chew it. Taking it at the same time each day can help you remember your dose.
Brigatinib can cause high blood pressure, even if you have never had it before. Your doctor will check your blood pressure before starting treatment, about 2 weeks after treatment begins, and then at least once every month to help detect and manage any changes early.
Brigatinib can rarely cause serious lung problems, especially during the first week of treatment. Contact your doctor immediately if you develop new or worsening shortness of breath, cough, chest discomfort, or difficulty breathing, as these symptoms need prompt medical evaluation.
Always tell your doctor about all prescription medicines, over-the-counter medicines, vitamins, herbal products, and dietary supplements before starting anything new. Some medicines, especially those that affect liver enzymes, can change how Brigatinib works and may require a dose adjustment or should be avoided.