Alpelisib
Written By Dr. Sakshi Jain
Reviewed By Dr. Rajeev SharmaLast updated 09 Sep 2026 | 10:17 AM (UTC)
Alpelisib Uses
Alpelisib is used in the treatment of breast cancer.
How Alpelisib works
Alpelisib works to treat cancer by blocking the signals that cause cancer cells to multiply, which helps to stop the spread of cancer cells.
Common side effects of Alpelisib
Fatigue, Increased glucose level in blood, Diarrhea, Rash, Nausea, Vomiting, Increased creatinine level in blood, Lymphocytopenia, Increased gamma-glutamyltransferase, Increased alanine aminotransferase, Decreased hemoglobin, Increased lipase in the blood, Decreased appetite, Stomatitis (Inflammation of the mouth), Weight loss, Hypoglycemia (low blood glucose level), Decreased calcium level in blood, Prolonged activated partial thromboplastin time (aPTT), Hair loss
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Expert advice for Alpelisib
- After starting your treatment with Alpelisib, you may be at risk of infection, so try to avoid crowds or people with colds. Report fever or any other signs of infection immediately to your doctor.
- Drink at least two to three-quarter fluid every 24 hours, unless you are instructed otherwise.
- To reduce nausea, take antinausea medications as prescribed by your doctor, and eat small, frequent meals.
- Inform your doctor if you notice any signs or symptoms of allergic reactions, like rash or shortness of breath, after taking Alpelisib.
- Monitor your sugar levels at intervals and report to your doctor if they are abnormally high. The doctor will be able to advise more on this.
- Eat foods that may help reduce diarrhea and take adequate rest.
- Use a soft toothbrush and rinse your mouth at least 3 times a day with saline water to help treat/prevent mouth sores.