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Allantoin + Clindamycin + Niacinamide

Written By Dr. Subita AlaghReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:37 AM (UTC)

Allantoin + Clindamycin + Niacinamide Uses

Allantoin+Clindamycin+Niacinamide is used in the treatment of acne.

How Allantoin + Clindamycin + Niacinamide works

Allantoin + Clindamycin + Niacinamide is a combination of three medicines: Allantoin , Clindamycin and Niacinamide which treat pimples (acne). Allantoin is a skin protectant which works as a moisturizer and relieves minor skin irritations. Clindamycin is an antibiotic which works by penetrating into the skin and killing acne-causing bacteria. Niacinamide is a form of vitamin B. It exerts anti-inflammatory effects when applied to the skin and reduces swelling, redness and tenderness associated with acne.

Common side effects of Allantoin + Clindamycin + Niacinamide

Skin peeling, Erythema (skin redness), Dry skin, Burning sensation at the site of application
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Expert advice for Allantoin + Clindamycin + Niacinamide

  • You may have to use it for a long time before your acne starts to improve. Be patient and keep using it every day.
  • Wash your skin with a mild cleanser and pat it dry before applying Allantoin + Clindamycin + Niacinamide.
  • Apply it as a thin layer onto clean, dry, unbroken skin affected by acne.
  • It may cause minor burning, stinging or irritation when applied. Inform your doctor if this does not go away.
  • Avoid contact with your eyes, nose or mouth. Rinse it off with water if you accidentally get the cream in these areas.
  • Dry skin is a common side effect. Use skin moisturizers and avoid alcohol-based products to avoid dryness.
  • Inform your doctor if symptoms do not get improves within 2-4 weeks of the treatment. 

Frequently asked questions for Allantoin + Clindamycin + Niacinamide

Usually, Allantoin+Clindamycin+Niacinamide starts working soon after applying it. However, it may take some days to kill all the harmful bacteria and make you feel better.
No, do not stop applying Allantoin+Clindamycin+Niacinamide and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.