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Pemetrexed

Written By Dr. Anuj SainiReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:34 AM (UTC)

Pemetrexed Uses

Pemetrexed is used in the treatment of non-small cell lung cancer and malignant pleural mesothelioma.

How Pemetrexed works

Pemetrexed interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.

Common side effects of Pemetrexed

Nausea, Vomiting, Sore throat, Loss of appetite, Stomatitis (Inflammation of the mouth), Hair loss, Low blood platelets, Rash, Fatigue, Anemia (low number of red blood cells), Diarrhea, Decreased white blood cell count (neutrophils), Neuropathy
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Expert advice for Pemetrexed

  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Frequently asked questions for Pemetrexed

No. Pemetrexed is not a vesicant.
Pemetrexed is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Yes. Pemetrexed is a prescription chemotherapy medication and hair loss is one of the possible side effects.