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Busulfan

Written By Dr. Subita AlaghReviewed By Dr. Rajeev Sharma
Last updated 28 Mar 2025 | 05:43 AM (UTC)

Busulfan Uses

Busulfan is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in combination with other cancer medicine during hematopoietic progenitor cell transplantation (HPCT).

How Busulfan works

Busulfan is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

Common side effects of Busulfan

Nausea, Vomiting, Abdominal pain, Anxiety, Decreased magnesium level in blood, Decreased potassium level in blood, Diarrhea, Fever, Headache, Increased glucose level in blood, Insomnia (difficulty in sleeping), Stomatitis (Inflammation of the mouth), Constipation, Depression, Dizziness, Myelosuppression, Rash, Weakness, Chills, Pain, Allergic reaction, Chest pain, Injection site inflammation, Back pain, Tachycardia, High blood pressure, Thromboembolism, Vasodilation, Decreased appetite, Dyspepsia, Dryness in mouth, Rectal discomfort, Abdominal distension, Decreased calcium level in blood, Increased bilirubin in the blood, Edema (swelling), Elevated serum glutamic pyruvic transaminase, Increased creatinine level in blood, Inflammation of the nose, Lung disorder, Cough, Nosebleeds, Breathlessness, Itching
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Expert advice for Busulfan

  • Busulfan is given as an injection into the vein by a healthcare provider.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • Your doctor may get regular blood tests done to monitor the levels of blood cells in your blood.
  • Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and sore throat.
     

Frequently asked questions for Busulfan

Yes, Busulfan can cause hair loss.
Yes. Busulfan is a vesicant (irritant).