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Asparaginase

Written By Dr. Subita AlaghReviewed By Dr. Rajeev Sharma
Last updated 23 May 2025 | 07:19 PM (UTC)

Asparaginase Uses

Asparaginase is used in the treatment of sickle cell anemia, prostate cancer, blood cancer (acute lymphocytic leukemia), soft tissue sarcoma and Hodgkin’s disease.

How Asparaginase works

Asparaginase belongs to class of medications called antineoplastic agents. Asparaginase is an enzyme that interferes with natural processes necessary for cancer cell growth, thereby killing or stopping the growth of cancer cells.
 

Common side effects of Asparaginase

Hypersensitivity, Thromboembolism
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Expert advice for Asparaginase

  • Asparaginase is given as an injection into the veins, muscles or under the skin by the healthcare provider.
  • It is advisable to drink plenty of fluids and stay hydrated while taking this medication.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • You may need to have blood tests to monitor your blood cells,  liver function and kidney function during treatment.
  • It can cause an increase in blood sugar levels. Hence, monitor your blood sugar level regularly.