Zyle 300mg Tablet

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Leeford Healthcare Ltd

Composition for Zyle 300mg Tablet

iconPrescription Required

Primarily used for

Potentiallyunsafewith
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Alcohol
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Pregnancy
52
₹5.2/Tablet
10 tablets in 1 strip
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Substitutes for Zyle Tablet

₹5.74/Tablet
10% costlier
₹6.81/Tablet
31% costlier
Zyloric 300mg Tablet
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Avery 300mg Tablet
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Alloric 300mg Tablet
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save 51%

Medicine Overview of Zyle Tablet

uses

Uses of Zyle Tablet

Zyle 300mg Tablet is used in the treatment of gout
It is a long-term treatment to lower blood uric acid levels and to prevent gout attacks. It also prevents and treats calcium kidney stones.
uses

Side effects of Zyle Tablet

Common

Skin rash.

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How to use Zyle Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It is better to take Zyle 300mg Tablet with food.

How Zyle Tablet works

Zyle 300mg tablet blocks the enzyme xanthine oxidase involved in the synthesis of uric acid and hence lowers the blood uric acid levels.

In Depth Information on Zyle Tablet

Expert advice for Zyle Tablet

  • Zyle is not a painkiller and it may take a few days to weeks before it starts working. You would need to take additional medicines to relieve your pain and inflammation during this time.
  • You may experience an increase in gouty attacks for first few weeks or months of taking Zyle. However, you must continue to take your medicine during these attacks.
  • Do not stop taking Zyle at once or without talking to your doctor as this may make gout worse.
  • Drink lots of water or fluids while taking Zyle to decrease the risk of kidney stone formation.
  • Get blood uric acid levels checked at regular intervals.
  • Get your liver function tests done before you start taking this medicine and whenever asked by your doctor as Zyle can affect your liver.
  • Zyle can make you feel drowsy. Avoid driving, use of machinery, or any activity that requires you to be alert.
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Warnings
Special precautions for Zyle 300mg Tablet
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Alcohol
CAUTION
Taking alcohol can affect the action of Zyle 300mg Tablet, i
ncrease your uric acid levels and hence aggravate gout.
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Pregnancy
WEIGH RISKS VS BENEFITS
Zyle 300mg Tablet may be unsafe to use during pregnancy.

Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
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Lactation
CAUTION
Zyle 300mg Tablet should be used with caution during lactati
on. Breast feeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
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Driving
Zyle 300mg Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.

It may cause somnolence, vertigo, and ataxia. Exercise caution if you have to drive or operate a machinery.
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Kidney
UNSAFE
Zyle 300mg Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.

Dose adjustment is required in patients with underlined renal diseases. Please consult your doctor.
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Liver
UNSAFE
Zyle 300mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

Dose adjustment is required in patients with underlined liver diseases. Please consult your doctor.
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Severely interacts with other drugs like
Tenof 300mg Tablet, Valten 300mg Tablet, Epsolin 50mg/2ml Injection, Eldapril 10mg Tablet

Missed Dosageuses

If you miss a dose of Allopurinol, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Patient Concerns

Frequently asked questions for Zyle 300mg Tablet

Frequently asked questions for Allopurinol

Zyle is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Zyle belongs to a group of medicines called xanthine oxidase inhibitors. It reduces the amount of uric acid in the body by blocking one of the processes that make it. It is used to treat gout (pain and swelling of the small joints due to elevated levels of uric acid in the blood and subsequent deposition in the joints), kidney stones, and to remove uric acid from the body in certain cancers.
Q. Can I take Zyle with Torasemide?
Zyle can be taken with Torasemide. Zyle is sometimes given to decrease the hyperuricemic effects of Torasemide. However, Zyle is not safe in patients with renal failure, so may need to be replaced with another similar medicine like febuxostat.
Q. How is Zyle different from febuxostat?
Both Zyle and febuxostat work in a similar way by lowering uric acid levels. However, as compared to Zyle, febuxostat is seen to be more effective and faster in its action. Also, in patients taking Zyle, a dose adjustment is needed if the patient has mild, moderate or severe renal failure while in the case of febuxostat a dose adjustment may be needed only in patients with severe renal failure.
Q. Can I take Zyle with febuxostat?
Both Zyle and febuxostat are uric acid lowering agents and work in a similar way. So, using both the two medicines together may not be very beneficial and can increase the risk of side effects. However, there have been studies where febuxostat when used with Zyle in patients with refractory gout, was quite effective in providing relief. So, a combined use would be best decided by your treating doctor depending on your condition.
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