Medicine Overview of Zyle Tablet
Zyle 300mg Tablet is used in the treatment of gout
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zyle 300mg Tablet is to be taken with food.
Zyle 300mg Tablet is a xanthine oxidase inhibitor. It works by decreasing blood uric acid, which is the chemical that causes gout.
In Depth Information on Zyle Tablet
- Your doctor has prescribed Zyle to reduce episodes of gout attack.
- Take Zyle at the same time every day, with or without food.
- Take plenty of fluids (2-3 litres) daily while on Zyle.
- Notify your doctor if you develop a rash. This could be a sign of allergy and should go away on discontinuing Zyle.
- When you first start taking Zyle, you might have more gout attacks. Do not stop Zyle on having an acute attack of gout as that could make an attack worse.
- To ensure that Zyle is working, you may have to undergo blood tests regularly.
Zyle Tablet related warnings
Taking alcohol can affect the action of Zyle 300mg Tablet, increase your uric acid levels and hence aggravate gout.
WEIGH RISKS VS BENEFITS
Zyle 300mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Zyle 300mg Tablet is safe to use during lactation.
Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Do not drive unless you are feeling well.
Occasionally drowsiness, dizziness or vertigo, ataxia and visual disturbances, may occur when taking Zyle 300mg Tablet. This may affect your driving ability.
Zyle 300mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Zyle 300mg Tablet may be needed. Please consult your doctor.
Zyle 300mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Zyle 300mg Tablet may be needed. Please consult your doctor.
If you miss a dose of Zyle 300mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Frequently asked questions about Zyle Tablet
Zyle is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Zyle belongs to a group of medicines called xanthine oxidase inhibitors. It reduces the amount of uric acid in the body by blocking one of the processes that make it. It is used to treat gout (pain and swelling of the small joints due to elevated levels of uric acid in the blood and subsequent deposition in the joints), kidney stones, and to remove uric acid from the body in certain cancers.
Q. Can I take Zyle with Torasemide?
Zyle can be taken with Torasemide. Zyle is sometimes given to decrease the hyperuricemic effects of Torasemide. However, Zyle is not safe in patients with renal failure, so may need to be replaced with another similar medicine like febuxostat.
Q. How is Zyle different from febuxostat?
Both Zyle and febuxostat work in a similar way by lowering uric acid levels. However, as compared to Zyle, febuxostat is seen to be more effective and faster in its action. Also, in patients taking Zyle, a dose adjustment is needed if the patient has mild, moderate or severe renal failure while in the case of febuxostat a dose adjustment may be needed only in patients with severe renal failure.
Q. Can I take Zyle with febuxostat?
Both Zyle and febuxostat are uric acid lowering agents and work in a similar way. So, using both the two medicines together may not be very beneficial and can increase the risk of side effects. However, there have been studies where febuxostat when used with Zyle in patients with refractory gout, was quite effective in providing relief. So, a combined use would be best decided by your treating doctor depending on your condition.
Severely interacts with other drugs like
Taking Zyle with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Medicines with composition Adefovir: Adesera
Medicines with composition Pyrazinamide: Zypara, Mzide, Antizide, Koxymide, Pza Ciba, Actizid, P Mide, Pyranij, Pyriza, Pyzina, Copyrazin, Piraldina, Zin LC, Pyralin, P-Zide, Pyz, Zypra, Pzn, Tbzide, Ticimide, Pizamax
Medicines with composition Didanosine: Dinex EC
Medicines with composition Capecitabine: Naprocap, Capnat, Xeloda, Cacit, Capiibine, Atubri, Capcel, Capetero, Distamine, Capxcel, Capecite, Capeta, Capezam, Caxeta, Xortib, Xabine, Captabin, Capecitaper, Citabin, Zocitab
Medicines with composition Telbivudine: Telbihep
Medicines with composition Carbamazepine: Carbatol, Sterop, Antilep, Versizur, Carbazep, Mezocar LA, Tegrital, Majerol, Mezapin, Carbesta, Shitol, Ezapin, Mazetol, Epnil, Versitol, Zigma, Carbin, Carbacontin, Zeptol, Epilent, Acetol, Tegril, Seizurone, Zepcar, Mezaril, Seizurone OX
Medicines with composition Captopril: Aceten
Medicines with composition Phenindione: Dindevan
Medicines with composition Phenytoin: Episol, Neptoin, C-Toin, Eptoin, Protoin, Pna, Seztin, Celetoin, Dilantin, Atoin, Phenos, M Toin, Phenykem, Epsod, Fentoin, Kiptoin, Solphen, Epicent, Phenytoin, Phentoin, Phetoin, Phalin
Medicines with composition Lisinopril: Lisinace, Lipril, Listril, Hipril, Lisoril, Linvas, Normopril, Odace, Acemin, Acinopril, Sopril, Lisitec, Fastril, L.P.L., Hypernil, Listen, Lapril
Medicines with composition Imidapril: Tanatril
Medicines with composition Ramipril: Ramifid, Ramace, Proace, Ramhop, Cordimil, R Pril, Ramicure, Ramipro, Ramil, Cardace, Ramcor, Etoril, Servace, Hopace, Rebeat, Rpm, Ramod, Ramiday, Ramveda, Zorem, Ramirica, Ramistar, Ramy 24, Variace, Ramfirst, Ramilace, Saface, Ramichek, Ramgee, Ramimerc, Ramp, Namipril, Hopecard, Ziram, Ramihart, Cardiopril, Odipril, Kapril, Polypril, Ecator, Ramipiril, RL, Ramifast, Eldapril, Bpace, Ramicard, Ramloz, Prilace, Preface, Ramitime, Ramitop, Ramey, Raminorm, Ramiril, Ramipres, Hopril, Ramisave, Zigpril, Heartace, Rugen, Ramic, Ramsho
Medicines with composition Enalapril: Envas, Minipril, EL, Enapril, Hytrol, Bql, Normace, Canvas, Tenam, Nuril, Enace, Enam, Encardil, Myoace, Vasopril, Canapril, Cardiril, Envapen, Lupinace, Oren, Enalap, Dilvas, Ena
Medicines with composition Theophylline: OD Phyllin, Onimar, Unicontin-E, Theobid, Theoday, Biryth, Klon T, Theoresp Plus, Lungfyl, Theolife, Phylobid, Uniresp, TR Phyllin, Theotas, Theoresp
Medicines with composition Acenocoumarol / Nicoumalone: Acethromb, Nicoz
Medicines with composition Tolbutamide: Rastinon
Medicines with composition Chlorpropamide: Diabinese
Medicines with composition Glipizide: Glyson, Lipi, Glynase, Glytop, Glucotrol, Glez, Diacon, Glibetic, Glyzip, Aviglip, Gluconil, Glylup, Semi Glynase, Glide
Medicines with composition Glimepiride: Secretag, Apriglim, Glisen, Xanapride, Glimpil, Gleam, Glypride, Zoryl, Glimpid, Dibiglim, Blisto, Glucoryl, Glimestar, Glimicure, Glimison, Flexiglim, Glimicon, Diaset, Prichek, Ozopride, Euglim, Glador, Glimisave, Diaglim, Glimer, Diapride, Glimy, Glimulin, Azulix, Betaglim, Glimfirst, Jubiglim, Geniride, Glimgold, Glimsite, Novapride, Diagli, Glimicut, Gepride, Glimcip, Adride, Xilia, Limer, GP MET (APOSTLE), Glucut, Gmr, Life Pride, Glimefide, Mepride, Gliway, Glamor, Hilglim, Glimidot, K-Glim, Glimda, Geminor, Diaswich, Gmp, Glimtide, Supride, Glimifix, Glyree, Glimiprex, Maydine, Zyvana, Gadz, Glimiprime, Glivio, GP MET(WEST COAST), Diaryl, Prides, Imediab, Lapride, Glimchek, Suseiz, Geeline, Glinorm, Glycirid, Glimcom, Glimenorm, Glimetis, Glimixia, Amaryl, Givov, Glimikem, Glynova, Glimtab, Ziglim, Isryl, Glusens, Glisto, Gala G, Glimetone, Glimz, Zorglim, Sulfoglim, Nuglim, Glimilife
Medicines with composition Gliclazide: Gliclan, Euclide, Gylis, Glykind, Gudiet, Glycosef, Nuzide, Glyloc, Dianorm, Reclide, Glytas, Glygard, Glycigon, Aviglic, Glurib, Glycinorm, Diamicron, DIABENT, Glicla, Diabend, Glix, Gzide, Azukon, Gazin, Gliva, Glicab, Safeline, Glimin, Glizid, Deb, Bioglide, Glicol, Gliza, Liz, Glicron, Glysiss, Glized, Hilglic, Mclazide, Glucoact, Glyup, Glz, Glyneed, Glycor, Glycitrol
Medicines with composition Indapamide: Natritor, Lorvas, Natrilix, Diurix, Insuretis, Inditor, Insuret, Indromide, Fanton, Indicontin, Indap, Divret
Medicines with composition Glibenclamide: D Con, Semi Daonil, Daonil, Semi-Euglucon, Aviglen, Glybovin, Gliconil, Diabetnil, Getrol, Glucosafe, Semi Codica, Afdiex, Euglucon
Medicines with composition Benzathine penicillin G: Benzathine
Medicines with composition Cyclosporine: Neoral, Consiral, Oncyclo, Panimun Bioral, Cyrin, Cyclophil ME, Sandimmun Neoral, Sandimmun, Graftin, Imusporin, Arpimune O
Medicines with composition Penicillin G / Benzylpenicillin: Sodicillin, Bistrepen, Fort.Proc.Pen, Pentids, Benzylpenicillin, Procaine, P.P.F, Pencip, Bpg, Fortified Procaine Penicillin, Pentas, Penidure, Fortified P.P
Medicines with composition Penicillin V / Phenoxymethyl penicillin: Kaypen
One of the following vendor pharmacies will deliver Zyle 300mg Tablet: BBS, SRG, ABP, DPL, CLT, ATP, SVH, AMR, UMP, JVO, NVY, JVN, MAK, GPT, SSA, ANT, AGT, ENP, DLP, RSA, SBL, BIO, VRS, HPC, OWP, HMP, OIP, AAY, PEN, TOM, DGN, TNH, MAX, KHH, USF, HBV, SHD, BDN, STA, PPR, SCH, SGC, HEX, LCC, GBL, SAF, RPP, JIV, DFP, OHM, ZEL, SDM, PVP, PLT, HAT, NVL, PNT, PTI, MPC, GNC, RSS, AVN, SWA, NSL, OLT, THP, MDO, SWP, JMJ, IAD, SYN, PRN, MMS, SAT, BMJ, RJH, RUS, LHA, EQN, RWP, SJP, WSI, HIP, ADT, NWP, ZVP, GPP, NNH, DPP, RKS, ARD, ATL, MAM, 9T9, NXG, RHW, SBA, BHP, BAL, AYU, PWN, SHP, MLC, DDR, FGH, GTK, EMB, MOM, RHL, AAR, INC, BTM, IPL, DYG, MSD, HGI, TRP, NTB, DHR, GTC, WHL, NDP, BSN