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Urofollitropin is used in the treatment of female infertility (inability to become pregnant) and male hypogonadism (decrease in male hormone)

How it works

FSH binds to the follicle stimulating hormone receptor which is a G-coupled transmembrane receptor. Binding of theFSH to its receptor seems to induce phosphorylation and activation of the PI3K (Phosphatidylinositol-3-kinase) and Akt signaling pathway, which is known to regulate many other metabolic and related survival/maturation functionsin cells.

Common side effects

Fatigue, Headache, Weight gain, Restlessness, Injection site pain, Hot flushes, Respiratory distress, Depression

Available Medicine

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Content on this page was last updated on 04 January, 2017, by Dr. Varun Gupta (MD Pharmacology)