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Trypsin is used to treat osteoarthritis, ulcers, wound cleansing and healing and to improve digestion.

How it works

Trypsin is an enzyme, which breaks down proteins into smaller fragments, thereby making it available for absorption into the blood. Trypsin when applied directly to wounds and ulcers removes dead tissue and improves healing.

Common side effects

Rash, Chest tightness, Shortness of breath, Itching, Mouth swelling, Pain, Stinging sensation, Burning sensation, Urticaria


No medicine available

Expert advice

  • Do not apply trypsin ointment to fresh blood clots.
  • Avoid contact of trypsin ointment with eyes.
  • Do not start or continue the trypsin tablets/ointment and consult your doctor: If you are pregnant, planning to become pregnant, or are breast-feeding, If you have a wound that contains fresh blood clot.

Frequently asked questions


Q. Is trypsin an enzyme, hormone, protein, endopeptidase?
Trypsin is an enzyme, a protein, an endopeptidase. Trypsin is not a hormone.
Q. Is trypsin acidic or basic?
Trypsin is neither acidic nor basic, it works on optimal operating pH of about 7.5-8.5.
Q. Is trypsin a zymogen, lipase?
Trypsin is a zymogen prior to activation. Trypsin is not a lipase.
Q. Is trypsin found in the stomach?
Yes, trypsin is found in the stomach.

Q. Does trypsin work in the stomach?
Yes, trypsin  works in the stomach.
Q. Is trypsin harmful?
Trypsin is not harmful if used as recommended. 

Q. Does trypsin kill cells?
Trypsin can damage the cells. In case, of any side effects, consult your doctor. 
Q. Does trypsin digest itself?
Trypsin digests itself.

Q. Does trypsin digest proteins?
Trypsin digests/breaks down proteins into smaller fragments.

Q. Does trypsin break down starch or fats?
 Trypsin does not breaks down starch or fats. Trypsin can digest itself.
Q. Does trypsin activate pepsinogen?
Trypsin does not activate pepsinogen. 

Q. Does trypsin cleave histidine?
Trypsin does not cleave histidine.
Q. Does trypsin require calcium?
In presence of the calcium trypsin remains stabilized which possess greater enzyme activity.

Content on this page was last updated on 17 October, 2016, by Dr. Varun Gupta (MD Pharmacology)