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Ticlopidine

INFORMATION

Uses

Ticlopidine is used in the treatment of heart attack.

How it works

Ticlopidine prevents platelets from sticking together which decreases the formation of harmful blood clots.

Common side effects

Bruise, Bleeding, Skin rash, Fever, Flatulence, Rash, Itching, Loss of appetite, Nausea, Sore throat, Headache, Stomach pain, Vomiting, Diarrhoea

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Frequently asked questions

Ticlopidine

Q.How does ticlopidine work?
Ticlopidine is a platelet aggregation inhibitor. Ticlopidine induces a dose dependent reduction in platelet aggregation by reducing platelet-fibrinogen binding and the platelet-platelet interactions thereby increasing the bleeding time. It thus works by preventing platelets from collecting and forming clots

Q.Is ticlopidine an anticoagulant?
No, ticlopidine is not an anticoagulant. It is an antiplatelet agent

Q.Is ticlopidine a prodrug?
Yes, ticlopidine is a prodrug that gets metabolized to its active form

Q.How is ticlopidine metabolized?
Ticlopidine is metabolized extensively by the liver

Q.What is ticlopidine is used for?
Ticlopidine is used to prevent to reduce the risk of thrombotic stroke (fatal or nonfatal) in patients who have experienced stroke mainly in patients who are intolerant or allergic to aspirin therapy or who have failed aspirin therapy. Ticlopidine may also be used as adjunctive therapy with aspirin in patients with coronary stent implantations.


Content on this page was last updated on 24 November, 2016, by Dr. Varun Gupta (MD Pharmacology)