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Thrombin is used to prevent surgical blood loss as well as minor bleeding/oozing. It is mainly used when the bleeding cannot be controlled by usual surgical techniques like suturing or ligation.

How it works

Thrombin belongs to a class of medicines called as hematologic agents. Thrombin is a protein involved in the production of blood clotting factors which prevents bleeding after cuts or surgery.

Common side effects

Numbness, Abnormal breathing, Abnormal vision, Allergic reaction, Anaphylactic reaction, Slurred speech, Weakness


No medicine available

Expert advice

  • Exercise caution if you are an elderly patient. 
  • Tell your doctor if you are pregnant or planning to become pregnant or are breastfeeding.
  • Do not take if you are allergic to thrombin or any of its ingredients.
  • Do not take if you have severe reactions to human blood products.
  • Do not give to patients with severe or brisk bleeding from the arteries.

Frequently asked questions


Q. Is thrombin a plasma protein or an enzyme?
Thrombin is an enzyme that converts fibrinogen to fibrin to form fibrin clot.

Content on this page was last updated on 04 October, 2016, by Dr. Varun Gupta (MD Pharmacology)