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Tamsulosin + Dutasteride

INFORMATION

Uses

Benign prostatic hyperplasia.

How it works

Tamsulosin is a selective ?-1 adrenoceptor blocker. It blocks ?-1 adrenoceptors, which are abundant in the prostate,prostatic capsule, prostatic urethra, and bladder neck, resulting relaxation of these adrenoceptors in the bladder neck and prostate. Thus, there is an improvement in urine flow rate and reduction in symptoms of benign prostatic hypertrophy (BPH). Dutasteride inhibits 5 ?-reductase, the enzyme responsible for conversion of testosterone to 5?-dihydrotestosterone (DHT). DHT appears to be the principal androgen responsible for stimulation of prostatic growth.

Common side effects

Pharyngitis, Postural hypotension (low blood pressure), Back pain, Breast tenderness, Breast enlargement, Chest pain, Cough, Decreased libido, Ejaculation disorder, Headache, Infection, Insomnia, Running nose, Sinus inflammation, Sleeping for unusually long periods, Weakness, Vertigo, Dizziness

AVAILABLE MEDICINE

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Content on this page was last updated on 17 May, 2016, by Dr. Varun Gupta (MD Pharmacology)