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For the treatment of urinary tract infection and chronic bronchitis.

How it works

Sulfametopyrazine is a competitive inhibitor of the bacterial enzyme dihydropteroate synthetase. Para-aminobenzoic acid (PABA), a substrateof the enzyme is prevented from binding. The inhibited reaction is necessary in these organisms for the synthesis of folic acid.

Common side effects

Neurological disturbances, Pulmonary eosinophilia, Diarrhoea, Fall in blood sugar level, Hypersensitivity reaction, Decreased level of thyroid hormones, Loss of appetite, Myocarditis (inflammation of heart muscle), Serum sickness, Vasculitis, Hepatomegaly, Liver necrosis


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Content on this page was last updated on 28 September, 2016, by Dr. Varun Gupta (MD Pharmacology)