Substituted Urea

Substituted Urea is used in the treatment of sickle cell anemia, prostate cancer, blood cancer (acute lymphocytic leukemia), soft tissue sarcoma and Hodgkin’s disease.

Substituted urea belongs to a class of drugs called as antimetabolites. It works by inhibiting cancer cell multiplication thus stopping the growth of cancer cells in the body. It also prevents the formation of sickle-shaped blood cells in patients with sickle cell anemia.

Breathlessness, Low blood platelets, Rash, Irritation of ear, Headache, Dizziness, Angioedema (swelling of deeper layers of skin), Injection site pain, Convulsion, Back pain, Edema (swelling), Increased heart rate, Oligospermia (low sperm count), Muscle pain, Pancreatic inflammation, Breast enlargement in male, Vomiting, Weakness, Allergic skin rash, Nausea, Decreased potassium level in blood, Abdominal pain, Indigestion, Loss of appetite, Decreased white blood cell count, Paresthesia (tingling or pricking sensation), Decreased red blood cell count, Fatigue, Increased liver enzymes, Fever, Anemia (low number of red blood cells), Hallucination, Itching, Bleeding, Chills, Urinary tract infection, Diarrhea, Increased creatine phosphokinase (CPK) level in blood, High blood pressure, Burning sensation, Decreased appetite, Feeling of discomfort, Megaloblastic anemia, Mucosal inflammation, Flushing (sense of warmth in the face, ears, neck and trunk), Low albumin level in blood, Hives, Decreased white blood cell count (neutrophils), Bruise, Constipation, Stomatitis (Inflammation of the mouth), Azoospermia (absence of sperms), Stomach ulcer, Increased glucose level in blood, Decreased blood pressure