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    Information about Sevelamer

    Sevelamer uses

    Sevelamer is used in the treatment of increased phosphate levels in blood. It is used in patients with kidney problems and on dialysis.

    How sevelamer works

    Sevelamer inhibits the absorption of phosphate from the intestine and lower the phosphate levels in the blood.

    Common side effects of sevelamer

    Nausea, Vomiting, Abdominal pain upper, Flatulence, Constipation, Diarrhea, Dyspepsia
    Content Details
    Written By
    Dr. Shreya Gupta
    MDS, BDS
    Reviewed By
    Dr. Ashish Ranjan
    MD (Pharmacology), MBBS
    Last updated on:
    18 Sep 2019 | 10:42 AM (IST)
    Want to know more?
    Read Our Editorial Policy

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    Expert advice for Sevelamer

    • Sevelamer is used to control blood phosphate level in patients that are on dialysis treatment.
    • You must take it with food and stick to the diet prescribed by your doctor.
    • You may develop low levels of calcium, folic acid, and vitamins A,D,E, and K in your blood. Your doctor may prescribe supplements, if necessary.
    • Avoid taking any other medicine 1 hour before or 3 hours after taking Sevelamer.
    • Inform your doctor if you have nausea, vomiting, constipation, pain in the abdomen, or if you have undergone any major stomach surgery.

    Frequently asked questions for Sevelamer


    Q. Is Sevelamer taken with food?

    Yes, Sevelamer can be taken with food. It is recommended to take 1-2 tablets (based on individual needs) thrice daily. It is important to take it with meals because Sevelamer works by binding to phosphate from food. Take it exactly as advised by your doctor.

    Q. Can Sevelamer be crushed?

    No, you should not crush, chew, or break Sevelamer into pieces. You should swallow it as a whole with water.

    Q. Why is it important for me to take Sevelamer?

    It is important to take Sevelamer as patients undergoing dialysis cannot control the phosphate levels in their blood, especially after a meal. When the level of phosphate exceeds above the range in the blood, it may cause problems such as itchy skin, red eyes, high blood pressure, bone pain, and also increase the risk of fractures. These increased serum phosphate levels are reduced by Sevelamer, as it binds phosphate from food in the digestive tract.

    Q. Does Sevelamer cause constipation?

    A common side effect of Sevelamer is constipation, though it does not occur in everyone. The other common side effects of stomach and intestine include diarrhea, indigestion, flatulence, and pain in abdomen. Immediately consult your doctor if these side effects become severe and disturb you.

    Q. Who should not take Sevelamer?

    Patients who are allergic to Sevelamer and who have low levels of phosphate in blood should avoid taking Sevelamer. Additionally, patients having intestinal obstruction should also avoid using Sevelamer.

    Q. Can I take ciprofloxacin while I am taking Sevelamer?

    Ciprofloxacin may interfere with the working of Sevelamer and therefore it should not be taken at the same time as Sevelamer. However, if taken together then a gap of at least 2 hours before or 6 hours after taking Sevelamer should be maintained.

    Q. How long do I need to take Sevelamer?

    Continue taking Sevelamer as long as recommended by your doctor. Sevelamer lowers your dietary phosphate levels but does not cure your disease. Hence, you may have to take it life long, as stopping Sevelamer may result in an increase in your phosphate levels.

    Q. Do I need to have any tests while taking Sevelamer?

    Yes, serum phosphate levels should be monitored regularly while you are taking Sevelamer. Also, the use of Sevelamer may decrease the levels of vitamin D, A, E, K, and folic acid and hence the levels need to be monitored during the treatment.

    Content on this page was last updated on 18 September, 2019, by Dr. Varun Gupta (MD Pharmacology)